Evidence map›Paper›PMID 33670618›Full record

ReviewDiagnostics (Basel, Switzerland)2021

Performance and Application of Commercially Available Loop-Mediated Isothermal Amplification (LAMP) Kits in Malaria Endemic and Non-Endemic Settings.

Ulrika Morris, Berit Aydin-Schmidt

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Five Hot Topics in Tropical Medicine: 2025.Infectious disease reports · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Remoscope: a label-free imaging cytometer for malaria diagnostics.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Circulation of Non-Open forum infectious diseases · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Genetic diversity ofEpidemiology and infection · 2023
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ulrika MorrisDepartment of Microbiology, Tumor, and Cell Biology, Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0003-4734-5754
Berit Aydin-SchmidtDepartment of Microbiology, Tumor, and Cell Biology, Karolinska Institutet, 17177 Stockholm, Sweden.
Karolinska Institutet · SE

Funding

Vetenskapsrådet 2017-05644
6 · The paper itself

Abstract

Loop-mediated isothermal amplification (LAMP) is a sensitive molecular tool suitable for use as a near point-of-care test for the diagnosis of malaria. Recent meta-analyses have detailed high sensitivity and specificity of malaria LAMP when compared to microscopy, rapid diagnostic tests, and polymerase chain reaction in both endemic and non-endemic settings. Despite this, the use of malaria LAMP has primarily been limited to research settings to date. In this review, we aim to assess to what extent commercially available malaria LAMP kits have been applied in different settings, and to identify possible obstacles that may have hindered their use from being adopted further. In order to address this, we conducted a literature search in PubMed.gov using the search terms (((LAMP) OR (Loop-mediated isothermal amplification)) AND ((Malaria) OR (Plasmodium))). Focusing primarily on studies employing one of the commercially available kits, we then selected three key areas of LAMP application for further review: the performance and application of LAMP in malaria endemic settings including low transmission areas; LAMP for malaria screening during pregnancy; and malaria LAMP in returning travelers in non-endemic settings.

Indexed as

LAMPloop-mediated isothermal amplificationlow transmissionmalariamalaria in pregnancynon-endemic settingPlasmodiumpre-eliminationreturning travelers

Identifiers

PMID33670618
PMCPMC7922894
OpenAlexW3130117825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.