Evidence map›Paper›PMID 33670593›Full record

ArticleMolecules (Basel, Switzerland)2021

Oxidative Stress Is Increased in Combined Oral Contraceptives Users and Is Positively Associated with High-Sensitivity C-Reactive Protein.

Sabina Cauci, Serena Xodo, Cinzia Buligan, Chiara Colaninno, Mattia Barbina, Giuseppe Barbina, Maria Pia Francescato

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
9.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
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  7. Article
  8. Review
  9. Combined Oral Contraceptives and the Risk of Thrombosis.International journal of molecular sciences · 2025
    Review
  10. Article
  11. Oral contraceptive pill phase alters mechanisms contributing to cutaneous microvascular function in response to local heating.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sabina CauciDepartment of Medicine, School of Medicine, University of Udine, 33100 Udine, Italy.
Serena XodoGynecology and Obstetrics Clinics, Maternal and Child Department, Santa Maria della Misericordia University-Hospital, 33100 Udine, Italy.ORCID 0000-0001-9756-0511
Cinzia BuliganDermatology Unit, Santa Maria della Misericordia University-Hospital, 33100 Udine, Italy.ORCID 0000-0002-4480-2027
Chiara ColaninnoDepartment of Medicine, School of Medicine, University of Udine, 33100 Udine, Italy.
Mattia BarbinaDepartment of Medicine, School of Medicine, University of Udine, 33100 Udine, Italy.
Giuseppe BarbinaClinical Analysis Laboratory, Department of Laboratory Medicine, Institute of Clinical Pathology, Santa Maria della Misericordia University-Hospital, 33100 Udine, Italy.
Maria Pia FrancescatoDepartment of Medicine, School of Medicine, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-7892-863X
University of Udine · ITOspedale Santa Maria della Misericordia di Udine · IT

Funding

Università degli Studi di Udine 2017-2018-2019
6 · The paper itself

Abstract

Information concerning the mechanisms underlying oxidative stress and low-grade inflammation in young healthy women predisposing eventually to future diseases is scarce. We investigated the relationship of oxidative stress and high-sensitivity C-reactive protein (hsCRP) in fertile-age women by oral combined contraceptive (OC) use. Caucasian Italian healthy non-obese women (

Indexed as

Oxidative StressAdolescentAdultBiomarkersContraceptives, Oral, CombinedC-Reactive ProteinHumansHydrogen PeroxideMiddle AgedRisk FactorsYoung AdultBiomarkersContraceptives, Oral, CombinedC-Reactive ProteinHydrogen Peroxidealimentary habitscontraceptive pillestrogenfree radicalshormonal contraceptioninflammationlipid peroxidationprogestinthird generation pillthromboembolism

Identifiers

PMID33670593
PMCPMC7921945
OpenAlexW3129312620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.