Evidence map›Paper›PMID 33670497›Full record

ArticleCancers2021

Targeting Mitochondria by SS-31 Ameliorates the Whole Body Energy Status in Cancer- and Chemotherapy-Induced Cachexia.

Riccardo Ballarò, Patrizia Lopalco, Valentina Audrito, Marc Beltrà, Fabrizio Pin, Roberto Angelini, Paola Costelli, Angela Corcelli, Andrea Bonetto, Hazel H Szeto and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
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  7. Article
  8. Review
  9. GL261 glioblastoma induces delayed body weight gain and stunted skeletal muscle growth in young mice.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  10. Diversity in chemotherapy-induced cachexia.American journal of physiology. Cell physiology · 2025
    Review
  11. Review
  12. Article
  13. Exploring heterogeneity: a dive into preclinical models of cancer cachexia.American journal of physiology. Cell physiology · 2024
    Review
  14. Metabolomics-driven discovery of therapeutic targets for cancer cachexia.Journal of cachexia, sarcopenia and muscle · 2024
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Recovery from FOLFOX chemotherapy-induced systemic and skeletal muscle metabolic dysfunction in mice.American journal of physiology. Endocrinology and metabolism · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Riccardo BallaròDepartment of Clinical and Biological Sciences, University of Torino, 10125 Torino, Italy.ORCID 0000-0001-5505-9024
Patrizia LopalcoDipartimento di Scienze Mediche di Base, Neuroscienze e Organi di Senso, University of Bari Aldo Moro, 70121 Bari, Italy.ORCID 0000-0003-3475-7485
Valentina AudritoMolecular Biotechnology Center, University of Torino, 10125 Torino, Italy.ORCID 0000-0002-5660-4175
Marc BeltràDepartment of Clinical and Biological Sciences, University of Torino, 10125 Torino, Italy.ORCID 0000-0001-6070-9861
Fabrizio PinDepartment of Anatomy, Cell Biology and Physiology, Indiana University, Indianapolis, IN 46202, USA.
Roberto AngeliniSwansea University Medical School, Swansea University, Swansea SA2 8PP, UK.ORCID 0000-0001-5136-5921
Paola CostelliDepartment of Clinical and Biological Sciences, University of Torino, 10125 Torino, Italy.
Angela CorcelliDipartimento di Scienze Mediche di Base, Neuroscienze e Organi di Senso, University of Bari Aldo Moro, 70121 Bari, Italy.ORCID 0000-0001-9658-8520
Andrea BonettoDepartment of Surgery, Indiana University, Indianapolis, IN 46202, USA.ORCID 0000-0002-3235-1871
Hazel H SzetoSocial Profit Network Research Lab, New York, NY 10016, USA.
Thomas M O'ConnellDepartment of Otolaryngology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.ORCID 0000-0003-4342-9539
Fabio PennaDepartment of Clinical and Biological Sciences, University of Torino, 10125 Torino, Italy.ORCID 0000-0002-2774-6027
University of Turin · ITIndiana University – Purdue University Indianapolis · USUniversity of Bari Aldo Moro · ITIndiana University School of MedicineSwansea University · GB

Funding

American Cancer Society 132013-RSG-18-010-01-CCGAssociazione Italiana per la Ricerca sul Cancro IG 2018-ID. 21963 projectUniversità degli Studi di Torino Ex-60% fundsV Foundation for Cancer Research V2017-021
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancer cachexialivermetabolomicsmitochondriamuscle wastingSS-31

Identifiers

PMID33670497
PMCPMC7923037
OpenAlexW3132897654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.