Evidence map›Paper›PMID 33670443›Full record

ArticleChildren (Basel, Switzerland)2021

The Feasibility of Studying Metabolites in PICU Multi-Organ Dysfunction Syndrome Patients over an 8-Day Course Using an Untargeted Approach.

Mara Leimanis-Laurens, Danny Gil, Andrew Kampfschulte, Claire Krohn, Elizabeth Prentice, Dominic Sanfilippo, Jeremy W Prokop, Todd A Lydic, Surender Rajasekaran

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Mara Leimanis-LaurensPediatric Critical Care Unit, Helen DeVos Children's Hospital, 100 Michigan Street NE, Grand Rapids, MI 49503, USA.ORCID 0000-0003-0595-4578
Danny GilPediatric Critical Care Unit, Helen DeVos Children's Hospital, 100 Michigan Street NE, Grand Rapids, MI 49503, USA.
Andrew KampfschulteSpectrum Health, 100 Michigan Street NE, Grand Rapids, MI 49503, USA.ORCID 0000-0001-9368-690X
Claire KrohnCollege of Human Medicine, Michigan State University, 15 Michigan Street NE, Grand Rapids, MI 49503, USA.
Elizabeth PrenticePediatric Critical Care Unit, Helen DeVos Children's Hospital, 100 Michigan Street NE, Grand Rapids, MI 49503, USA.
Dominic SanfilippoPediatric Critical Care Unit, Helen DeVos Children's Hospital, 100 Michigan Street NE, Grand Rapids, MI 49503, USA.
Jeremy W ProkopDepartment of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Life Sciences Building, 1355 Bogue Street, East Lansing, MI 48824, USA.
Todd A LydicDepartment of Physiology, Collaborative Mass Spectrometry Core, Michigan State University, 578 S. Shaw Ln. Chemistry Building, East Lansing, MI 48824, USA.
Surender RajasekaranPediatric Critical Care Unit, Helen DeVos Children's Hospital, 100 Michigan Street NE, Grand Rapids, MI 49503, USA.
Helen DeVos Children's Hospital · USMichigan State University · USSpectrum Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolites are generated from critical biological functions and metabolism. This pediatric study reviewed plasma metabolites in patients suffering from multi-organ dysfunction syndrome (MODS) in the pediatric intensive care unit (PICU) using an untargeted metabolomics approach. Patients meeting the criteria for MODS were screened for eligibility and consented (

Indexed as

blood plasmaextracorporeal membrane oxygenationliquid chromatography–mass spectrometrymetabolitesmultiple organ dysfunction syndromepediatric intensive care unit

Identifiers

PMID33670443
PMCPMC7922853
OpenAlexW3132424528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.