Evidence map›Paper›PMID 33670421›Full record

ArticleInternational journal of molecular sciences2021

Cold Adaptation in Antarctic Notothenioids: Comparative Transcriptomics Reveals Novel Insights in the Peculiar Role of Gills and Highlights Signatures of Cobalamin Deficiency.

Federico Ansaloni, Marco Gerdol, Valentina Torboli, Nicola Reinaldo Fornaini, Samuele Greco, Piero Giulio Giulianini, Maria Rosaria Coscia, Andrea Miccoli, Gianfranco Santovito, Francesco Buonocore and 2 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The physiological significance of plasma-accessible carbonic anhydrase in the respiratory systems of fishes.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Federico AnsaloniDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0002-6344-4931
Marco GerdolDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-6411-0813
Valentina TorboliDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.
Nicola Reinaldo FornainiDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.
Samuele GrecoDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0003-3435-2656
Piero Giulio GiulianiniDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-5356-7754
Maria Rosaria CosciaInstitute of Biochemistry and Cell Biology, National Research Council of Italy, 80131 Naples, Italy.
Andrea MiccoliDepartment for Innovation in Biological, Agro-Food and Forest Systems, University of Tuscia, 01100 Viterbo, Italy.ORCID 0000-0002-4545-7229
Gianfranco SantovitoDepartment of Biology, University of Padua, 35131 Padua, Italy.ORCID 0000-0001-8260-7006
Francesco BuonocoreDepartment for Innovation in Biological, Agro-Food and Forest Systems, University of Tuscia, 01100 Viterbo, Italy.ORCID 0000-0001-8045-5651
Giuseppe ScapigliatiDepartment for Innovation in Biological, Agro-Food and Forest Systems, University of Tuscia, 01100 Viterbo, Italy.ORCID 0000-0001-9730-9394
Alberto PallaviciniDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.
University of Trieste · ITUniversità degli Studi della Tuscia · ITNational Research Council · ITScuola Internazionale Superiore di Studi Avanzati · ITUniversity of Padua · IT

Funding

Italian Program of Antarctic Research PNRA16_00099
6 · The paper itself

Abstract

Far from being devoid of life, Antarctic waters are home to Cryonotothenioidea, which represent one of the fascinating cases of evolutionary adaptation to extreme environmental conditions in vertebrates. Thanks to a series of unique morphological and physiological peculiarities, which include the paradigmatic case of loss of hemoglobin in the family Channichthyidae, these fish survive and thrive at sub-zero temperatures. While some of the distinctive features of such adaptations have been known for decades, our knowledge of their genetic and molecular bases is still limited. We generated a reference de novo assembly of the icefish

Indexed as

AcclimatizationFishesTranscriptomeVitamin B 12 DeficiencyAnimalsAntarctic RegionsGillsVitamin B 12Vitamin B 12Antarcticacold adaptationCryonotothenioideaRNA-seqtranscobalamin

Identifiers

PMID33670421
PMCPMC7918649
OpenAlexW3127479279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.