Evidence map›Paper›PMID 33670420›Full record

ArticleInternational journal of molecular sciences2021

Nanopore Sequencing Resolves Elusive Long Tandem-Repeat Regions in Mitochondrial Genomes.

Liina Kinkar, Robin B Gasser, Bonnie L Webster, David Rollinson, D Timothy J Littlewood, Bill C H Chang, Andreas J Stroehlein, Pasi K Korhonen, Neil D Young

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. Genomic insights intoMicrobiology spectrum · 2026
    Article
  2. Article
  3. The complete mitochondrial genome of the parasitoidMitochondrial DNA. Part B, Resources · 2026
    Article
  4. Long-read sequencing reveals that the mitochondrial genome of an individualCurrent research in parasitology & vector-borne diseases · 2026
    Article
  5. Article
  6. Mitochondrial Genomes of the Blood FlukesPathogens (Basel, Switzerland) · 2025
    Article
  7. Article
  8. The Mitogenome of the Haecon-5 Strain ofInternational journal of molecular sciences · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Multichromosomal Mitochondrial Genome ofInternational journal of molecular sciences · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Liina KinkarDepartment of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Robin B GasserDepartment of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Bonnie L WebsterDepartment of Life Sciences, Natural History Museum, London SW7 5BD, UK.ORCID 0000-0003-0930-9314
David RollinsonDepartment of Life Sciences, Natural History Museum, London SW7 5BD, UK.ORCID 0000-0003-1999-1716
D Timothy J LittlewoodDepartment of Life Sciences, Natural History Museum, London SW7 5BD, UK.ORCID 0000-0002-2718-4001
Bill C H ChangDepartment of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Andreas J StroehleinDepartment of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0001-9432-9816
Pasi K KorhonenDepartment of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Neil D YoungDepartment of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
The University of Melbourne · AUNatural History Museum · GB

Funding

Australian Research Council LP180101085Australian Research Council LP180101334
6 · The paper itself

Abstract

Long non-coding, tandem-repetitive regions in mitochondrial (mt) genomes of many metazoans have been notoriously difficult to characterise accurately using conventional sequencing methods. Here, we show how the use of a third-generation (long-read) sequencing and informatic approach can overcome this problem. We employed Oxford Nanopore technology to sequence genomic DNAs from a pool of adult worms of the carcinogenic parasite,

Indexed as

Genome, HelminthGenome, MitochondrialNanopore SequencingTandem Repeat SequencesAnimalsSchistosoma haematobiuminformaticsmitochondrial (mt) genomenon-coding (control) regionOxford Nanopore technologySchistosoma haematobiumtandem-repetitive DNA

Identifiers

PMID33670420
PMCPMC7918261
OpenAlexW3127228657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.