Evidence map›Paper›PMID 33670249›Full record

ArticleVaccines2021

Construction and Immunogenicity Comparison of Three Virus-Like Particles Carrying Different Combinations of Structural Proteins of Avian Coronavirus Infectious Bronchitis Virus.

Yu Zhang, Yuan Yuan, Li-Hua Zhang, Dan Zhu, Lu Wang, Lan-Ping Wei, Wen-Sheng Fan, Chang-Run Zhao, Yan-Jing Su, Jian-Qi Liao and 4 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Yu ZhangCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Yuan YuanCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Li-Hua ZhangCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Dan ZhuCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Lu WangCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Lan-Ping WeiCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Wen-Sheng FanCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Chang-Run ZhaoCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Yan-Jing SuCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Jian-Qi LiaoCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Lu YongCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Tian-Chao WeiCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Ping WeiCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Mei-Lan MoCollege of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Guangxi University · CN

Funding

Guangxi Natural Science Foundation Grants 2018GXNSFAA281009, 2019GXNSFAA245009Guangxi Special Funding on Science and Technology Research AA17204057Nanning Scientific Research and Technology Development Project 20182024-1National Natural Science Foundation of China 31860715
6 · The paper itself

Abstract

Infectious bronchitis virus (IBV) poses massive economic losses in the global poultry industry. Here, we firstly report the construction and immunogenicity comparison of virus-like particles (VLPs) carrying the S, M and E proteins (SME-VLPs); VLPs carrying the S and M proteins (SM-VLPs); and VLPs carrying the M and E proteins (ME-VLPs) from the dominant serotype representative strain GX-YL5 in China. The neutralizing antibody response induced by the SME-VLPs was similar to that induced by the inactivated oil vaccine (OEV) of GX-YL5, and higher than those induced by the SM-VLPs, ME-VLPs and commercial live vaccine H120. More importantly, the SME-VLPs elicited higher percentages of CD4

Indexed as

constructionimmunogenicityinfectious bronchitis virusvirus-like particles

Identifiers

PMID33670249
PMCPMC7918244
OpenAlexW3127203534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.