Evidence map›Paper›PMID 33670148›Full record

ArticleInternational journal of environmental research and public health2021

Urinary Bisphenol A, F and S Levels and Semen Quality in Young Adult Danish Men.

Thea Emily Benson, Anne Gaml-Sørensen, Andreas Ernst, Nis Brix, Karin Sørig Hougaard, Katia Keglberg Hærvig, Jens Peter Ellekilde Bonde, Sandra Søgaard Tøttenborg, Christian H Lindh, Cecilia Høst Ramlau-Hansen and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
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  3. Endocrine Disrupting Agents: Toxicological Aspects on Male Reproduction.Reproductive sciences (Thousand Oaks, Calif.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Thea Emily BensonDepartment of Public Health, Research Unit for Epidemiology, Aarhus University, 8000 Aarhus, Denmark.
Anne Gaml-SørensenDepartment of Public Health, Research Unit for Epidemiology, Aarhus University, 8000 Aarhus, Denmark.ORCID 0000-0002-5242-939X
Andreas ErnstDepartment of Public Health, Research Unit for Epidemiology, Aarhus University, 8000 Aarhus, Denmark.
Nis BrixDepartment of Public Health, Research Unit for Epidemiology, Aarhus University, 8000 Aarhus, Denmark.
Karin Sørig HougaardDepartment of Public Health, The Faculty of Health Sciences, University of Copenhagen, 1014 Copenhagen, Denmark.
Katia Keglberg HærvigDepartment of Public Health, The Faculty of Health Sciences, University of Copenhagen, 1014 Copenhagen, Denmark.
Jens Peter Ellekilde BondeDepartment of Public Health, The Faculty of Health Sciences, University of Copenhagen, 1014 Copenhagen, Denmark.
Sandra Søgaard TøttenborgDepartment of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, 2400 Copenhagen, Denmark.ORCID 0000-0001-7742-4360
Christian H LindhDivision of Occupational and Environmental Medicine, Lund University, 22363 Lund, Sweden.ORCID 0000-0001-7435-9890
Cecilia Høst Ramlau-HansenDepartment of Public Health, Research Unit for Epidemiology, Aarhus University, 8000 Aarhus, Denmark.
Gunnar ToftDepartment of Clinical Medicine, Department of Clinical Epidemiology, Aarhus University, 8200 Aarhus, Denmark.
Aarhus University · DKUniversity of Copenhagen · DKFrederiksberg Hospital · DKLund University · SESteno Diabetes Centers · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphenol A (BPA) is considered an endocrine disruptor and has been associated with deleterious effects on spermatogenesis and male fertility. Bisphenol F (BPF) and S (BPS) are structurally similar to BPA, but knowledge of their effects on male fertility remains limited. In this cross-sectional study, we investigated the associations between exposure to BPA, BPF, and BPS and semen quality in 556 men 18-20 years of age from the Fetal Programming of Semen Quality (FEPOS) cohort. A urine sample was collected from each participant for determination of BPA, BPF, and BPS concentrations while a semen sample was collected to determine ejaculate volume, sperm concentration, total sperm count, sperm motility, and sperm morphology. Associations between urinary bisphenol levels (continuous and quartile-divided) and semen characteristics were estimated using a negative binomial regression model adjusting for urine creatinine concentration, alcohol intake, smoking status, body mass index (BMI), fever, sexual abstinence time, maternal pre-pregnancy BMI, and first trimester smoking, and highest parental education during first trimester. We found no associations between urinary bisphenol of semen quality in a sample of young men from the general Danish population.

Indexed as

Semen AnalysisSperm MotilityBenzhydryl CompoundsBisphenol A CompoundsCross-Sectional StudiesDenmarkFemaleHumansMalePhenolsPregnancyYoung AdultBenzhydryl Compoundsbisphenol ABisphenol A CompoundsPhenolsbisphenolendocrine disruptorepidemiologymale fertilitysemen quality

Identifiers

PMID33670148
PMCPMC7916849
OpenAlexW3127424914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.