Evidence map›Paper›PMID 33670145›Full record

ArticleInternational journal of environmental research and public health2021

Telomere Shortening and Accelerated Aging in US Military Veterans.

Jeffrey T Howard, Jud C Janak, Alexis R Santos-Lozada, Sarah McEvilla, Stephanie D Ansley, Lauren E Walker, Avron Spiro, Ian J Stewart

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Jeffrey T HowardDepartment of Public Health, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA.
Jud C JanakBexar Data LLC, San Antonio, TX 78210, USA.
Alexis R Santos-LozadaDepartment of Human Development and Family Studies, Pennsylvania State University, 119 Health and Human Development Building, University Park, PA 16802, USA.ORCID 0000-0002-8437-4493
Sarah McEvillaDepartment of Public Health, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA.
Stephanie D AnsleyDepartment of Public Health, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA.
Lauren E WalkerDavid Grant USAF Medical Center, Travis Air Force Base, Fairfield, CA 94535, USA.
Avron SpiroMassachusetts Veterans Epidemiology Research and Information Center, VA Boston Healthcare System, Boston, MA 02130, USA.ORCID 0000-0003-4080-8621
Ian J StewartUniformed Services University of Health Sciences, Bethesda, MD 20814, USA.
The University of Texas at San Antonio · USBexar County Medical Examiner's Office · USBoston University · USDavid Grant USAF Medical Center · USPennsylvania State University · USUniformed Services University of the Health Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A growing body of literature on military personnel and veterans' health suggests that prior military service may be associated with exposures that increase the risk of cardiovascular disease (CVD), which may differ by race/ethnicity. This study examined the hypothesis that differential telomere shortening, a measure of cellular aging, by race/ethnicity may explain prior findings of differential CVD risk in racial/ethnic groups with military service. Data from the first two continuous waves of the National Health and Nutrition Examination Survey (NHANES), administered from 1999-2002 were analyzed. Mean telomere length in base pairs was analyzed with multivariable adjusted linear regression with complex sample design, stratified by sex. The unadjusted mean telomere length was 225.8 base shorter for individuals with prior military service. The mean telomere length for men was 47.2 (95% CI: -92.9, -1.5;

Indexed as

VeteransAgingCellular SenescenceFemaleHumansLeukocytesMaleNutrition SurveysTelomere Shorteningaccelerated agingtelomeresveteran’s health

Identifiers

PMID33670145
PMCPMC7916830
OpenAlexW3129171499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.