Evidence map›Paper›PMID 33670014›Full record

ArticlePolymers2021

Nanoparticle-Hydrogel Composite Drug Delivery System for Potential Ocular Applications.

Xuan-Ling Hsu, Lien-Chen Wu, Jui-Yang Hsieh, Yi-You Huang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Xuan-Ling HsuDepartment of Biomedical Engineering, National Taiwan University, Taipei 10051, Taiwan.
Lien-Chen WuDepartment of Orthopaedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.
Jui-Yang HsiehDepartment of Biomedical Engineering, National Taiwan University, Taipei 10051, Taiwan.
Yi-You HuangDepartment of Biomedical Engineering, National Taiwan University, Taipei 10051, Taiwan.
National Taiwan University · TWNational Taiwan University Hospital · TWTaipei Medical University · TW

Funding

Ministry of Science and Technology MOST 109-2221-E-002-048
6 · The paper itself

Abstract

Intravitreal injections are clinically established procedures in the treatment of posterior eye diseases, such as wet age-related macular degeneration (wet AMD) which requires monthly intravitreal injections of anti-vascular endothelial growth factor (anti-VEGF) protein drugs that can lead to complications due to frequent dosing. In this study, we designed a composite drug delivery system (DDS) consisting of drug-loaded poly (lactide-

Indexed as

composite drug delivery systemhyaluronaninjectable hydrogelnanoparticlePLGA

Identifiers

PMID33670014
PMCPMC7927131
OpenAlexW3131039269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.