Evidence map›Paper›PMID 33669882›Full record

ArticleNutrients2021

Cardiorespiratory Fitness Predicted by Fibrinogen and Leptin Concentrations in Children with Obesity and Risk for Diabetes: A Cross-Sectional Study and a ROC Curve Analysis.

Kyriaki Tsiroukidou, Elpis Hatziagorou, Maria G Grammatikopoulou, Anastasios Vamvakis, Kalliopi Kontouli, Christos Tzimos, John Tsanakas, Bessie E Spiliotis

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Obesity-Related Coagulation Activation in Adolescents and Children: A Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Pooled it
  2. Article
  3. Article
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  6. Review
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  8. Article
  9. Health risk assessment of PMScientific reports · 2021
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Kyriaki Tsiroukidou3rd Department of Pediatrics, Hippokration General Hospital, 49 Konstantinoupoleos Str, Aristotle University of Thessaloniki, GR-54642 Thessaloniki, Greece.
Elpis Hatziagorou3rd Department of Pediatrics, Hippokration General Hospital, 49 Konstantinoupoleos Str, Aristotle University of Thessaloniki, GR-54642 Thessaloniki, Greece.
Maria G Grammatikopoulou3rd Department of Pediatrics, Hippokration General Hospital, 49 Konstantinoupoleos Str, Aristotle University of Thessaloniki, GR-54642 Thessaloniki, Greece.ORCID 0000-0003-4167-6595
Anastasios Vamvakis3rd Department of Pediatrics, Hippokration General Hospital, 49 Konstantinoupoleos Str, Aristotle University of Thessaloniki, GR-54642 Thessaloniki, Greece.ORCID 0000-0001-8101-0857
Kalliopi Kontouli3rd Department of Pediatrics, Hippokration General Hospital, 49 Konstantinoupoleos Str, Aristotle University of Thessaloniki, GR-54642 Thessaloniki, Greece.
Christos TzimosNorthern Greece Statistics Directorate, Hellenic Statistical Authority, GR-54646 Thessaloniki, Greece.ORCID 0000-0003-2842-2320
John Tsanakas3rd Department of Pediatrics, Hippokration General Hospital, 49 Konstantinoupoleos Str, Aristotle University of Thessaloniki, GR-54642 Thessaloniki, Greece.
Bessie E SpiliotisPaediatric Endocrine Research Laboratory, Division of Paediatric Endocrinology and Diabetes, Department of Paediatrics, School of Medicine, University of Patras, University Campus, GR-26504 Patras, Greece.
Aristotle University of Thessaloniki · GRHellenic Statistical Authority · GRInternational Hellenic University · GRUniversity of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is defined as abnormal or excessive fat accumulation that presents a risk to health. The ability to exercise is affected by adiposity, and this mechanism involves low-grade chronic inflammation and homeostatic stress produced mainly in adipocytes, which can result in abnormal adipokine secretion. To date, the gold standard for cardiorespiratory fitness assessment is considered to be the maximum oxygen uptake (VO

Indexed as

AdiponectinAdolescentBlood GlucoseCardiorespiratory FitnessCase-Control StudiesChildCross-Sectional StudiesDiabetes MellitusExercise TestFemaleFibrinogenHumansInsulinLeptinMaleObesityAdiponectinBlood GlucoseFibrinogenInsulinLeptinadipositycardiopulmonary testchildhoodCPETexercisehigh-sensitive CRPinsulin resistancemetabolic healthnutritionobeseoverweightVO2max

Identifiers

PMID33669882
PMCPMC7923274
OpenAlexW3129212200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.