Evidence map›Paper›PMID 33669849›Full record

ArticleInternational journal of molecular sciences2021

Dysfunctional Gut Microbiome Networks in Childhood IgE-Mediated Food Allergy.

Khui Hung Lee, Jing Guo, Yong Song, Amir Ariff, Michael O'Sullivan, Belinda Hales, Benjamin J Mullins, Guicheng Zhang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
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  4. Impact of oral immunotherapy on diversity of gut microbiota in food-allergic children.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Khui Hung LeeSchool of Public Health, Curtin University of Technology, Bentley, WA 6102, Australia.ORCID 0000-0001-5906-4664
Jing GuoSchool of Public Health, Curtin University of Technology, Bentley, WA 6102, Australia.
Yong SongThe Menzies Institute for Medical Research, University of Tasmania, 17 Liverpool St, Hobart, TAS 7000, Australia.
Amir AriffSchool of Women's and Children's Health, University of New South Wales, Sydney, NSW 2052, Australia.
Michael O'SullivanDepartment of Immunology, Perth Children's Hospital, Nedlands, WA 6009, Australia.ORCID 0000-0001-7896-2697
Belinda HalesTelethon Kids Institute, University of Western Australia, West Perth, WA 6872, Australia.
Benjamin J MullinsSchool of Public Health, Curtin University of Technology, Bentley, WA 6102, Australia.
Guicheng ZhangSchool of Public Health, Curtin University of Technology, Bentley, WA 6102, Australia.ORCID 0000-0001-9888-5385
Curtin University · AUPrincess Margaret Hospital for Children · AUThe Kids Research Institute Australia · AUThe University of Western Australia · AUUniversity of Tasmania · AUUNSW Sydney · AU

Funding

Australian Government Research Training Program Stipend Scholarship (RTP)Telethon-Perth Children's Hospital Research Fund (TPCHRF)
6 · The paper itself

Abstract

The development of food allergy has been reported to be related with the changes in the gut microbiome, however the specific microbe associated with the pathogenesis of food allergy remains elusive. This study aimed to comprehensively characterize the gut microbiome and identify individual or group gut microbes relating to food-allergy using 16S rRNA gene sequencing with network analysis. Faecal samples were collected from children with IgE-mediated food allergies (

Indexed as

Gastrointestinal MicrobiomeBiodiversityChildDiscriminant AnalysisFemaleFood HypersensitivityHumansImmunoglobulin EMalePhylogenyImmunoglobulin E16S rRNA gene sequencingfood allergymicrobiomeRuminococcaceaeWGCNA

Identifiers

PMID33669849
PMCPMC7923212
OpenAlexW3132907304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.