Evidence map›Paper›PMID 33669814›Full record

ArticleMicroorganisms2021

In Vitro Analysis of the Antioxidant and Antiviral Activity of Embelin against Herpes Simplex Virus-1.

Tony Elias, Lee H Lee, Miriam Rossi, Francesco Caruso, Sandra D Adams

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Recent advances in anti-infective drug discovery · 2025
    Article
  4. Emerging drugs for the treatment of herpetic keratitis.Expert opinion on emerging drugs · 2024
    Review
  5. Article
  6. Therapeutic Potential of Biochanin A in Herpes Simplex Keratitis.Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  7. Review
  8. Article
  9. Comments about theInternational journal of molecular sciences · 2022
    Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tony EliasDepartment of Biology, Montclair State University, Montclair, NJ 07043, USA.
Lee H LeeDepartment of Biology, Montclair State University, Montclair, NJ 07043, USA.
Miriam RossiDepartment of Chemistry, Vassar College, Poughkeepsie, NY 12604, USA.ORCID 0000-0001-9609-474X
Francesco CarusoDepartment of Chemistry, Vassar College, Poughkeepsie, NY 12604, USA.
Sandra D AdamsDepartment of Biology, Montclair State University, Montclair, NJ 07043, USA.ORCID 0000-0003-4260-0576
Montclair State University · USVassar College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes simplex virus-1 (HSV-1) causes a wide range of infections from mild to life-threatening in the human population. There are effective treatments for HSV-1 infections that are limited due HSV-1 latency and development of resistance to current therapeutics. The goal of this study was to investigate the antioxidant and antiviral effects of embelin on HSV-1 in cultured Vero cells. Oxidative stress was verified by an extensive production of a reactive oxygen species (ROS) H

Indexed as

antioxidantantiviralembelinHSV-1

Identifiers

PMID33669814
PMCPMC7922599
OpenAlexW3132995746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.