Evidence map›Paper›PMID 33669808›Full record

ReviewInternational journal of molecular sciences2021

Elvira Forte, Micheal A McLellan, Daniel A Skelly, Nadia A Rosenthal

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elvira ForteThe Jackson Laboratory, Bar Harbor, ME 04609, USA.ORCID 0000-0002-5555-9122
Micheal A McLellanThe Jackson Laboratory, Bar Harbor, ME 04609, USA.ORCID 0000-0003-1946-5038
Daniel A SkellyThe Jackson Laboratory, Bar Harbor, ME 04609, USA.ORCID 0000-0002-2329-2216
Nadia A RosenthalThe Jackson Laboratory, Bar Harbor, ME 04609, USA.

Funding

Interventions That Retard Mammalian AgingU01AG022308 · NIA · JACKSON LABORATORY · PI Ronny Korstanje · 2003 to 2026
$30.5M
Understanding the role of thyroid hormone signaling during axolotl limb regenerationP20GM104318 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI DRUMMOND, IAIN A. · 2013 to 2023
$23.0M
Using the Collaborative Cross to Understand the Impact of a High-Fat Diet on the Adipose Tissue Invariant Natural Killer T Cell CompartmentR21AI145383 · NIAID · JACKSON LABORATORY · PI SKELLY, DANIEL A · 2019 to 2020
$468k
Fondation Leducq 13CVD01NIH/NCI 5 P30 CA034196NIH/NIA 5 U01 AG022308-17NIH/NIAID 5 R21 AI145383NIH/NIGMS 2 P20 GM104318
6 · The paper itself

Abstract

Recent technological advances have revolutionized the study of tissue biology and garnered a greater appreciation for tissue complexity. In order to understand cardiac development, heart tissue homeostasis, and the effects of stress and injury on the cardiovascular system, it is essential to characterize the heart at high cellular resolution. Single-cell profiling provides a more precise definition of tissue composition, cell differentiation trajectories, and intercellular communication, compared to classical bulk approaches. Here, we aim to review how recent single-cell multi-omic studies have changed our understanding of cell dynamics during cardiac development, and in the healthy and diseased adult myocardium.

Indexed as

Single-Cell AnalysisAnimalsCardiovascular SystemCellular ReprogrammingCOVID-19Embryonic DevelopmentHumansTranscriptomecardiacdevelopmentdifferentiationheartinjuryregenerationscRNAseqsingle-cell

Identifiers

PMID33669808
PMCPMC7922347

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.