Evidence map›Paper›PMID 33669793›Full record

ArticleBiomolecules2021

Behavioral Effects of Developmental Exposure to JWH-018 in Wild-Type and Disrupted in Schizophrenia 1 (

Judit García-González, Bruno de Quadros, William Havelange, Alistair J Brock, Caroline H Brennan

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Exploring Cannabinoid Effects Using Zebrafish (International journal of molecular sciences · 2025
    Review
  5. bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Zebrafish as an Animal Model in Cannabinoid Research.International journal of molecular sciences · 2023
    Review
  9. iScience · 2023
    Article
  10. Article
  11. A comparative analysis ofFrontiers in behavioral neuroscience · 2022
    Article
  12. Frontiers in neuroscience · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Judit García-GonzálezSchool of Biological and Chemical Sciences, Queen Mary, University of London, London E1 4NS, UK.
Bruno de QuadrosSchool of Biological and Chemical Sciences, Queen Mary, University of London, London E1 4NS, UK.
William HavelangeSchool of Biological and Chemical Sciences, Queen Mary, University of London, London E1 4NS, UK.
Alistair J BrockLeica Biosystems Newcastle Ltd, Newcastle NE12 8EW, UK.
Caroline H BrennanSchool of Biological and Chemical Sciences, Queen Mary, University of London, London E1 4NS, UK.ORCID 0000-0002-4169-4083
Queen Mary University of London · GBDanaher (United Kingdom) · GB

Funding

Exploiting zebrafish genetics to identify genes affecting addiction-related phenotypes.U01DA044400 · NIDA · UNIV/LONDON-QUEEN MARY& WESTFIELD COLL · PI BRENNAN, CAROLINE HELEN, BUSCH-NENTWICH, ELISABETH MARIE · 2018 to 2022
$2.0M
Biotechnology and Biological Sciences Research Council BB/M007863National Centre for the Replacement Refinement and Reduction of Animals in Research G1000053National Centre for the Replacement, Refinement and Reduction of Animals in Research G1000053/1NIDA NIH HHS U01 DA044400NIH HHS U01 DA044400-03
6 · The paper itself

Abstract

Synthetic cannabinoids can cause acute adverse psychological effects, but the potential impact when exposure happens before birth is unknown. Use of synthetic cannabinoids during pregnancy may affect fetal brain development, and such effects could be moderated by the genetic makeup of an individual. Disrupted in schizophrenia 1 (

Indexed as

Gene Expression Regulation, DevelopmentalAcousticsAllelesAnimalsAnxietyBehavior, AnimalCannabinoidsDronabinolFemaleIndolesMaternal ExposureModels, GeneticMovementMutationNaphthalenesNerve Tissue Proteins1-pentyl-3-(1-naphthoyl)indoleCannabinoidsDISC1 protein, zebrafishDronabinolIndolesNaphthalenesNerve Tissue ProteinsNicotineZebrafish Proteinsanxietycannabinoidsdisc1forced light/dark assayJWH-018zebrafish

Identifiers

PMID33669793
PMCPMC7922669
OpenAlexW3132124501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.