Evidence map›Paper›PMID 33669712›Full record

ArticleMolecules (Basel, Switzerland)2021

Antimicrobial Effect and Cytotoxic Evaluation of Mg-Doped Hydroxyapatite Functionalized with Au-Nano Rods.

Domenico Franco, Giovanna Calabrese, Salvatore Petralia, Giulia Neri, Carmelo Corsaro, Lucia Forte, Stefano Squarzoni, Salvatore Guglielmino, Francesco Traina, Enza Fazio and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Domenico FrancoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98166 Messina, Italy.ORCID 0000-0002-2104-5465
Giovanna CalabreseDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98166 Messina, Italy.
Salvatore PetraliaDepartment of Drug Science and Health, University of Catania, 95125 Catania, Italy.
Giulia NeriDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98166 Messina, Italy.ORCID 0000-0002-4458-0022
Carmelo CorsaroDepartment of Mathematical and Computational Sciences, Physics Science and Earth Science, University of Messina, 98166 Messina, Italy.ORCID 0000-0002-1497-8750
Lucia ForteFin-Ceramica Faenza, 48018 Faenza, Italy.
Stefano SquarzoniCNR-Institute of Molecular Genetics "Luigi Luca Cavalli-Sforza", 40136 Bologna, Italy.ORCID 0000-0001-6538-5923
Salvatore GuglielminoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98166 Messina, Italy.
Francesco TrainaIRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Enza FazioDepartment of Mathematical and Computational Sciences, Physics Science and Earth Science, University of Messina, 98166 Messina, Italy.ORCID 0000-0001-9132-7073
Sabrina ConociDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98166 Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydroxyapatite (HA) is the main inorganic mineral that constitutes bone matrix and represents the most used biomaterial for bone regeneration. Over the years, it has been demonstrated that HA exhibits good biocompatibility, osteoconductivity, and osteoinductivity both in vitro and in vivo, and can be prepared by synthetic and natural sources via easy fabrication strategies. However, its low antibacterial property and its fragile nature restricts its usage for bone graft applications. In this study we functionalized a MgHA scaffold with gold nanorods (AuNRs) and evaluated its antibacterial effect against

Indexed as

Anti-Infective AgentsCell DeathCell SurvivalDurapatiteEscherichia coliGoldHumansMagnesiumMicrobial Sensitivity TestsNanotubesPhotoelectron SpectroscopyStaphylococcus aureusTissue ScaffoldsAnti-Infective AgentsDurapatiteGoldMagnesiumantibacterial activityAu nanoparticlesbone tissue engineeringcytotoxicityhybrid biomaterialshydroxyapatitenano-functionalization

Identifiers

PMID33669712
PMCPMC7923154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.