Evidence map›Paper›PMID 33669651›Full record

ArticleBrain sciences2021

Beyond Reading Modulation: Temporo-Parietal tDCS Alters Visuo-Spatial Attention and Motion Perception in Dyslexia.

Giulia Lazzaro, Sara Bertoni, Deny Menghini, Floriana Costanzo, Sandro Franceschini, Cristiana Varuzza, Luca Ronconi, Andrea Battisti, Simone Gori, Andrea Facoetti and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04964427 (The Effects of Methylphenidate), which is not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04964427 nacompletednot on this map

The Effects of Methylphenidate (MPH) and Non-invasive Brain Stimulation (tDCS) on Inhibitory Control Children With Attention-Deficit/Hyperactivity Disorder (ADHD)

TypeinterventionalSponsorBambino Gesù Hospital and Research InstituteRan2021 to 2022Enrolled26ConditionsAttention Deficit Hyperactivity DisorderArmsMethylphenidate, anodal tDCS, sham tDCS
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Giulia LazzaroChild and Adolescent Psychiatry Unit, Department of Neuroscience, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Sara BertoniDepartment of Human and Social Science, University of Bergamo, 24129 Bergamo, Italy.ORCID 0000-0002-0985-0373
Deny MenghiniChild and Adolescent Psychiatry Unit, Department of Neuroscience, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.ORCID 0000-0002-8418-9570
Floriana CostanzoChild and Adolescent Psychiatry Unit, Department of Neuroscience, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.ORCID 0000-0002-0877-9691
Sandro FranceschiniDepartment of General Psychology, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-2326-6800
Cristiana VaruzzaChild and Adolescent Psychiatry Unit, Department of Neuroscience, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Luca RonconiSchool of Psychology, University "Vita-Salute San Raffaele", 20132 Milano, Italy.
Andrea BattistiChild and Adolescent Psychiatry Unit, Department of Neuroscience, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Simone GoriDepartment of Human and Social Science, University of Bergamo, 24129 Bergamo, Italy.
Andrea FacoettiDepartment of General Psychology, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-4626-6213
Stefano VicariChild and Adolescent Psychiatry Unit, Department of Neuroscience, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Bambino Gesù Children's Hospital · ITUniversity of Bergamo · ITUniversity of Padua · ITLibera Università Maria SS. Assunta · ITUniversità Cattolica del Sacro Cuore · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dyslexia is a neurodevelopmental disorder with an atypical activation of posterior left-hemisphere brain reading networks (i.e., temporo-occipital and temporo-parietal regions) and multiple neuropsychological deficits. Transcranial direct current stimulation (tDCS) is a tool for manipulating neural activity and, in turn, neurocognitive processes. While studies have demonstrated the significant effects of tDCS on reading, neurocognitive changes beyond reading modulation have been poorly investigated. The present study aimed at examining whether tDCS on temporo-parietal regions affected not only reading, but also phonological skills, visuo-spatial working memory, visuo-spatial attention, and motion perception in a polarity-dependent way. In a within-subjects design, ten children and adolescents with dyslexia performed reading and neuropsychological tasks after 20 min of exposure to Left Anodal/Right Cathodal (LA/RC) and Right Anodal/Left Cathodal (RA/LC) tDCS. LA/RC tDCS compared to RA/LC tDCS improved text accuracy, word recognition speed, motion perception, and modified attentional focusing in our group of children and adolescents with dyslexia. Changes in text reading accuracy and word recognition speed-after LA/RC tDCS compared to RA/LC-were related to changes in motion perception and in visuo-spatial working memory, respectively. Our findings demonstrated that reading and domain-general neurocognitive functions in a group of children and adolescents with dyslexia change following tDCS and that they are polarity-dependent.

Indexed as

attentionbrain reading networkschildren and adolescentscortical excitabilitymagnocellular-dorsal pathwayneural noiseneuromodulation

Identifiers

PMID33669651
PMCPMC7922381
OpenAlexW3131022485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.