Evidence map›Paper›PMID 33669627›Full record

ReviewMolecules (Basel, Switzerland)2021

Antifungal Properties of Essential Oils and Their Compounds for Application in Skin Fungal Infections: Conventional and Nonconventional Approaches.

Aswir Abd Rashed, Devi-Nair Gunasegavan Rathi, Nor Atikah Husna Ahmad Nasir, Ahmad Zuhairi Abd Rahman

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06417983 (Use of Topical Essential Oil Compound to Treat Toe Nail Onychomycosis), which is not on this map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
12.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06417983 unknown statusnot on this mapstarted 2024, after this paper: background citation

Use of Topical Essential Oil Compound to Treat Toe Nail Onychomycosis

TypeobservationalSponsorMedical Life Care Planners, LLCRan2024 to 2024Enrolled50ConditionsOnychomycosis of Toenail, Fungal Infection, Toenail Infection
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. IndigenousFrontiers in microbiology · 2026
    Article
  9. TargetingInternational journal of molecular sciences · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Synergistic potential and apoptosis induction ofCurrent medical mycology · 2025
    Article
  15. Article
  16. Review
  17. Review
  18. Antifungal Activity of Tea Tree (Journal of fungi (Basel, Switzerland) · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Aswir Abd RashedNutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia No.1, Jalan Setia Murni U13/52, Seksyen U13 Setia Alam, Shah Alam 40170, Malaysia.ORCID 0000-0002-2380-8171
Devi-Nair Gunasegavan RathiNutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia No.1, Jalan Setia Murni U13/52, Seksyen U13 Setia Alam, Shah Alam 40170, Malaysia.ORCID 0000-0002-6885-1712
Nor Atikah Husna Ahmad NasirDepartment of Biology, Faculty of Applied Science, Universiti Teknologi MARA (Perlis Branch), Arau 02600, Malaysia.
Ahmad Zuhairi Abd RahmanCancer Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, No.1, Jalan Setia Murni U13/52, Seksyen U13 Setia Alam, Shah Alam 40170, Malaysia.ORCID 0000-0002-6489-5072
Ministry of Health · MYUniversiti Teknologi MARA · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Essential oils (EOs) are known to have varying degrees of antimicrobial properties that are mainly due to the presence of bioactive compounds. These include antiviral, nematicidal, antifungal, insecticidal and antioxidant properties. This review highlights the potential of EOs and their compounds for application as antifungal agents for the treatment of skin diseases via conventional and nonconventional approaches. A search was conducted using three databases (Scopus, Web of Science, Google Scholar), and all relevant articles from the period of 2010-2020 that are freely available in English were extracted. In our findings, EOs with a high percentage of monoterpenes showed strong ability as potential antifungal agents.

Indexed as

AnimalsAntifungal AgentsDermatomycosesHumansOils, VolatilePublicationsAntifungal AgentsOils, Volatileessential oilsinterventionin vitroin vivoskin fungus

Identifiers

PMID33669627
PMCPMC7922942
OpenAlexW3129475934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.