Evidence map›Paper›PMID 33669624›Full record

ReviewCancers2021

The Value of Real-World Data in Understanding Prostate Cancer Risk and Improving Clinical Care: Examples from Swedish Registries.

Kerri Beckmann, Hans Garmo, Ingela Franck Lissbrant, Pär Stattin

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Kerri BeckmannCancer Epidemiology and Population Health Research Group, Allied Health and Human Performance, University of South Australia, Adelaide, SA 5001, Australia.
Hans GarmoTranslational Oncology and Urology Research, School of Cancer and Pharmaceutical Studies, Kings College London, London SE1 9RT, UK.
Ingela Franck LissbrantDepartment of Oncology, Institute of Clinical Sciences, Sahlgrenska University, SE-41345 Gothenburg, Sweden.ORCID 0000-0001-8612-9814
Pär StattinDepartment of Surgical Sciences, Uppsala Hospital University, SE-75185 Uppsala, Sweden.ORCID 0000-0002-8306-0687
Uppsala University Hospital · SESahlgrenska University Hospital · SEUniversity of South Australia · AU

Funding

Cancerfonden 2019 0030Swedish Research Council 2017-00847The Swedish Association of Local Authorities 2019/01469
6 · The paper itself

Abstract

Real-world data (RWD), that is, data from sources other than controlled clinical trials, play an increasingly important role in medical research. The development of quality clinical registers, increasing access to administrative data sources, growing computing power and data linkage capacities have contributed to greater availability of RWD. Evidence derived from RWD increases our understanding of prostate cancer (PCa) aetiology, natural history and effective management. While randomised controlled trials offer the best level of evidence for establishing the efficacy of medical interventions and making causal inferences, studies using RWD offer complementary evidence about the effectiveness, long-term outcomes and safety of interventions in real-world settings. RWD provide the only means of addressing questions about risk factors and exposures that cannot be "controlled", or when assessing rare outcomes. This review provides examples of the value of RWD for generating evidence about PCa, focusing on studies using data from a quality clinical register, namely the National Prostate Cancer Register (NPCR) Sweden, with longitudinal data on advanced PCa in Patient-overview Prostate Cancer (PPC) and data linkages to other sources in Prostate Cancer data Base Sweden (PCBaSe).

Indexed as

administrative dataclinical registrymanagementprostate cancerreal-world datarisk

Identifiers

PMID33669624
PMCPMC7923148
OpenAlexW3133378502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.