Evidence map›Paper›PMID 33669500›Full record

ArticleAnimals : an open access journal from MDPI2021

Arginine Alters miRNA Expression Involved in Development and Proliferation of Rat Mammary Tissue.

Gang Zhou, Qiaoyun Xu, Feifan Wu, Mengzhi Wang, Lianmin Chen, Liangyu Hu, Jingwen Zhao, Juan J Loor, Jun Zhang

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Gang ZhouHuaiyin Institute of Agricultural Sciences in Xuhuai Regio, Huaian 223000, China.
Qiaoyun XuCollege of Animal Science and Technology, Yangzhou University, 88 South University Ave., Yangzhou 225009, China.
Feifan WuCollege of Animal Science and Technology, Yangzhou University, 88 South University Ave., Yangzhou 225009, China.
Mengzhi WangCollege of Animal Science and Technology, Yangzhou University, 88 South University Ave., Yangzhou 225009, China.
Lianmin ChenCollege of Animal Science and Technology, Yangzhou University, 88 South University Ave., Yangzhou 225009, China.ORCID 0000-0003-0660-3518
Liangyu HuCollege of Animal Science and Technology, Yangzhou University, 88 South University Ave., Yangzhou 225009, China.
Jingwen ZhaoCollege of Animal Science and Technology, Yangzhou University, 88 South University Ave., Yangzhou 225009, China.
Juan J LoorDepartment of Animal Sciences and Division of Nutritional Sciences, University of Illinois, 1207 W Gregory Drive, Urbana, IL 61801, USA.ORCID 0000-0003-1586-4365
Jun ZhangCollege of Animal Science and Technology, Yangzhou University, 88 South University Ave., Yangzhou 225009, China.
Yangzhou University · CNHuaiyin Institute of Technology · CNUniversity Medical Center Groningen · NLUniversity of Illinois Urbana-Champaign · US

Funding

Development Fund HNY201927General project of natural science research in Universities of Jiangsu Province 19KJB230003National Natural Science Foundation of China 31902127Natural Science Foundation of China 31672446Natural Science Foundation of Jiangsu Province BK20141270
6 · The paper itself

Abstract

This study was designed to determine the effects of dietary arginine on development and proliferation in rat mammary tissue through changes in miRNA profiles. Twelve pregnant Wistar rats were allocated randomly to two groups. A basal diet containing arginine or the control diet containing glutamate on an equal nitrogen basis as the arginine supplemented diet were used. The experiment included a pre-experimental period of four days before parturition and an experimental period of 17 days after parturition. Mammary tissue was collected for histology, RNA extraction and high-throughput sequencing analysis. The greater mammary acinar area indicated that arginine supplementation enhanced mammary tissue development (

Indexed as

argininemammarymiRNAsrat

Identifiers

PMID33669500
PMCPMC7923093
OpenAlexW3129333157

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.