Evidence map›Paper›PMID 33669495›Full record

ArticleJournal of clinical medicine2021

Is Urinary Netrin-1 a Good Marker of Tubular Damage in Preterm Newborns?

Monika Kamianowska, Marek Szczepański, Natalia Chomontowska, Justyna Trochim, Anna Wasilewska

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Monika KamianowskaDepartment of Neonatology and Neonatal Intensive Care, Medical University of Bialystok, 15-276 Bialystok, Poland.
Marek SzczepańskiDepartment of Neonatology and Neonatal Intensive Care, Medical University of Bialystok, 15-276 Bialystok, Poland.
Natalia ChomontowskaDepartment of Neonatology and Neonatal Intensive Care, Medical University of Bialystok, 15-276 Bialystok, Poland.
Justyna TrochimDepartment of Pediatric Laboratory Diagnostics, Medical University of Bialystok, 15-276 Bialystok, Poland.
Anna WasilewskaDepartment of Pediatrics and Nephrology, Medical University of Bialystok, 15-276 Bialystok, Poland.
Medical University of Białystok · PL

Funding

Medical University of Bialystok, Poland SUB/1/DN/19/001/3305
6 · The paper itself

Abstract

There is a lack of a good marker for early kidney injury in premature newborns. In recent publications, netrin-1 seems to be a promising biomarker of kidney damage in different pathological states. The study aimed to measure the urinary level of netrin-1 depending on gestational age. A prospective study involved 88 newborns (I-60 premature newborns, II-28 healthy term newborns). Additionally, premature babies were divided for 2 groups: IA-28 babies born between 30-34 weeks of gestation and IB-32 born at 35-36 weeks. The median urinary concentration of netrin-1 was: IA-(median, Q1-Q3) 63.65 (56.57-79.92) pg/dL, IB-61.90 (58.84-67.17) pg/dL, and II-60.37 (53.77-68.75) pg/dL, respectively. However urinary netrin-1 normalized by urinary concentration of creatinine were IA-547.9 (360.2-687.5) ng/mg cr., IB-163.64 (119.15-295.96) ng/mg cr., and II-81.37 (56.84-138.58) ng/mg cr., respectively and differ significantly between the examined groups (

Indexed as

netrin-1premature newbornsrenal tubular damage

Identifiers

PMID33669495
PMCPMC7922412
OpenAlexW3130937229

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.