Evidence map›Paper›PMID 33669456›Full record

ReviewInternational journal of molecular sciences2021

Adjunctive Nutraceutical Therapies for COVID-19.

Lalita Subedi, Stephanie Tchen, Bhakta Prasad Gaire, Bingren Hu, Kurt Hu

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
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  6. Article
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  8. Article
  9. Article
  10. Article
  11. ERC-BiP Functional Protein Pathway for Assessing Endoplasmic Reticulum Stress Induced by SARS-CoV-2 Replication after Cell Invasion.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Article
  12. Review
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  19. Review
  20. Development of Antioxidant and Nutritious Lentil (Foods (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lalita SubediSchool of Medicine, University of Maryland, Baltimore, MD 21201, USA.ORCID 0000-0003-4851-7650
Stephanie TchenFroedtert Hospital, Milwaukee, WI 53226, USA.
Bhakta Prasad GaireSchool of Medicine, University of Maryland, Baltimore, MD 21201, USA.
Bingren HuSchool of Medicine, University of Maryland, Baltimore, MD 21201, USA.
Kurt HuDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.ORCID 0000-0002-2859-8513
University of Maryland, Baltimore · USFroedtert Hospital · USMedical College of Wisconsin · US

Funding

Novel anti-NPC aggregation strategy against brain ischemia-reperfusion injuryR01NS097875 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI HU, BINGREN · 2017 to 2021
$1.7M
Change in NSF ATPase activity Leads to Brain Ischemia Reperfusion InjuryR01NS102815 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI HU, BINGREN · 2018 to 2023
$1.7M
The Role of Lysosomal Membrane Permeabilization and Cathepsin B Release in Stroke Brain InjuryR01NS129553 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Bingren Hu · 2023 to 2026
$1.5M
NINDS NIH HHS R01 NS097875NINDS NIH HHS R01 NS102815NINDS NIH HHS R01 NS129553
6 · The paper itself

Abstract

The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2/COVID-19), is a worldwide pandemic, as declared by the World Health Organization (WHO). It is a respiratory virus that infects people of all ages. Although it may present with mild to no symptoms in most patients, those who are older, immunocompromised, or with multiple comorbidities may present with severe and life-threatening infections. Throughout history, nutraceuticals, such as a variety of phytochemicals from medicinal plants and dietary supplements, have been used as adjunct therapies for many disease conditions, including viral infections. Appropriate use of these adjunct therapies with antiviral proprieties may be beneficial in the treatment and/or prophylaxis of COVID-19. In this review, we provide a comprehensive summary of nutraceuticals, such as vitamins C, D, E, zinc, melatonin, and other phytochemicals and function foods. These nutraceuticals may have potential therapeutic efficacies in fighting the threat of the SARS-CoV-2/COVID-19 pandemic.

Indexed as

COVID-19 Drug TreatmentDietary SupplementsAnimalsAntiviral AgentsAscorbic AcidFunctional FoodHumansMelatoninSARS-CoV-2Vitamin DVitamin EVitaminsZincAntiviral AgentsAscorbic AcidMelatoninVitamin DVitamin EVitaminsZincantiviral therapynovel coronavirusnutraceuticalspandemicviral infection

Identifiers

PMID33669456
PMCPMC7920448
OpenAlexW3130068528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.