Evidence map›Paper›PMID 33669384›Full record

ReviewBiomolecules2021

DNA Methylation, Mechanisms of

Veronica Nobile, Cecilia Pucci, Pietro Chiurazzi, Giovanni Neri, Elisabetta Tabolacci

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 46 citations in OpenAlex.

  1. DNA Methylation ofEnvironment & health (Washington, D.C.) · 2026
    Article
  2. Article
  3. Article
  4. NAR molecular medicine · 2026
    Article
  5. Review
  6. Genes · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Epigenetic insights into Fragile X Syndrome.Frontiers in cell and developmental biology · 2024
    Review
  17. CGG repeat expansion in LRP12 in amyotrophic lateral sclerosis.American journal of human genetics · 2023
    Article
  18. Review
  19. International journal of molecular sciences · 2023
    Article
  20. Narrative Review: Update on the Molecular Diagnosis of Fragile X Syndrome.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Veronica NobileSezione di Medicina Genomica, Dipartimento Scienze della Vita e Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Cecilia PucciSezione di Medicina Genomica, Dipartimento Scienze della Vita e Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Pietro ChiurazziSezione di Medicina Genomica, Dipartimento Scienze della Vita e Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0001-5104-1521
Giovanni NeriSezione di Medicina Genomica, Dipartimento Scienze della Vita e Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0001-7642-0130
Elisabetta TabolacciSezione di Medicina Genomica, Dipartimento Scienze della Vita e Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-4707-2242
Università Cattolica del Sacro Cuore · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca Prot. 201789LFKBMinistero dell'Istruzione, dell'Università e della Ricerca University Grant D.1
6 · The paper itself

Abstract

Among the inherited causes of intellectual disability and autism, Fragile X syndrome (FXS) is the most frequent form, for which there is currently no cure. In most FXS patients, the

Indexed as

DNA MethylationEpigenesis, GeneticGene SilencingAnimalsEpigenomicsFemaleFragile X Messenger Ribonucleoprotein 1Fragile X SyndromeGene Expression ProfilingGene Expression RegulationHumansMaleMutationPhenotypePromoter Regions, GeneticTranscription, GeneticFMR1 protein, humanFragile X Messenger Ribonucleoprotein 1DNA methylationepigenetic modificationsFMR1 genefragile X syndromegene expression signatures

Identifiers

PMID33669384
PMCPMC7920310
OpenAlexW3130501390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.