Evidence map›Paper›PMID 33669317›Full record

ArticleJournal of clinical medicine2021

Neutrophil-to-Lymphocyte Ratio Is a Useful Marker for Predicting Histological Types of Early Gastric Cancer.

Sho Yasui, Tomoaki Takata, Yu Kamitani, Yukari Mae, Hiroki Kurumi, Yuichiro Ikebuchi, Akira Yoshida, Koichiro Kawaguchi, Kazuo Yashima, Hajime Isomoto

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sho YasuiDivision of Gastroenterology and Nephrology, Faculty of Medicine, Tottori University, Tottori 683-8504, Japan.
Tomoaki TakataDivision of Gastroenterology and Nephrology, Faculty of Medicine, Tottori University, Tottori 683-8504, Japan.ORCID 0000-0003-2959-6015
Yu KamitaniDivision of Gastroenterology and Nephrology, Faculty of Medicine, Tottori University, Tottori 683-8504, Japan.
Yukari MaeDivision of Gastroenterology and Nephrology, Faculty of Medicine, Tottori University, Tottori 683-8504, Japan.
Hiroki KurumiDivision of Gastroenterology and Nephrology, Faculty of Medicine, Tottori University, Tottori 683-8504, Japan.ORCID 0000-0002-2372-1631
Yuichiro IkebuchiDivision of Gastroenterology and Nephrology, Faculty of Medicine, Tottori University, Tottori 683-8504, Japan.ORCID 0000-0003-1672-8584
Akira YoshidaDivision of Gastroenterology and Nephrology, Faculty of Medicine, Tottori University, Tottori 683-8504, Japan.ORCID 0000-0002-7299-4257
Koichiro KawaguchiDivision of Gastroenterology and Nephrology, Faculty of Medicine, Tottori University, Tottori 683-8504, Japan.
Kazuo YashimaDivision of Gastroenterology and Nephrology, Faculty of Medicine, Tottori University, Tottori 683-8504, Japan.
Hajime IsomotoDivision of Gastroenterology and Nephrology, Faculty of Medicine, Tottori University, Tottori 683-8504, Japan.
Tottori University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe indications for endoscopic submucosal dissection (ESD) for gastric cancer are based on preoperative histological assessment; however, examination of tissue biopsy is not always reliable as only a limited portion of the lesion can be obtained. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are markers of inflammatory response and are potentially associated with the grade of malignancy in gastric cancer. We aimed to investigate the association between NLR and PLR and the histology of gastric cancer.

methodsThis study included 218 patients who underwent ESD for gastric cancer. The relationship between NLR/PLR and histological diagnosis was investigated.

resultsPatients with adenocarcinomas showed significantly higher NLR and PLR than those with adenomas (

conclusionThis study suggests that NLR could be a useful marker for assessing early gastric cancer.

Indexed as

endoscopic submucosal dissection (ESD)gastric cancerneutrophil-to-lymphocyte ratio (NLR)platelet-to-lymphocyte ratio (PLR)

Identifiers

PMID33669317
PMCPMC7920243
OpenAlexW3133269625

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.