Evidence map›Paper›PMID 33669312›Full record

ArticleMolecules (Basel, Switzerland)2021

Anti-Inflammatory, Antidiabetic Properties and In Silico Modeling of Cucurbitane-Type Triterpene Glycosides from Fruits of an Indian Cultivar of

Wilmer H Perera, Siddanagouda R Shivanagoudra, Jose L Pérez, Da Mi Kim, Yuxiang Sun, Guddadarangavvanahally K Jayaprakasha, Bhimanagouda S Patil

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Three Pairs of Novel Enantiomeric 8-International journal of molecular sciences · 2022
    Article
  4. Review
  5. Ethnobotanical Survey on Bitter Tea in Taiwan.Frontiers in pharmacology · 2022
    Article
  6. Review
  7. Frontiers in pharmacology · 2022
    Review
  8. Article
  9. Inhibitory Effects of Cucurbitane-Type Triterpenoids fromMolecules (Basel, Switzerland) · 2021
    Article
  10. Review
  11. BioMed research international · 2021
    Article
  12. Review
  13. Three Selected Edible Crops of the GenusFrontiers in pharmacology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wilmer H PereraVegetable and Fruit Improvement Center, Department of Horticultural Sciences, Texas A&M University, 1500 Research Parkway, Suite A120, College Station, TX 77843, USA.ORCID 0000-0003-3607-8638
Siddanagouda R ShivanagoudraVegetable and Fruit Improvement Center, Department of Horticultural Sciences, Texas A&M University, 1500 Research Parkway, Suite A120, College Station, TX 77843, USA.
Jose L PérezVegetable and Fruit Improvement Center, Department of Horticultural Sciences, Texas A&M University, 1500 Research Parkway, Suite A120, College Station, TX 77843, USA.
Da Mi KimDepartment of Nutrition, Texas A&M University, College Station, TX 77843, USA.
Yuxiang SunDepartment of Nutrition, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0002-6656-3733
Guddadarangavvanahally K JayaprakashaVegetable and Fruit Improvement Center, Department of Horticultural Sciences, Texas A&M University, 1500 Research Parkway, Suite A120, College Station, TX 77843, USA.ORCID 0000-0003-1749-9699
Bhimanagouda S PatilVegetable and Fruit Improvement Center, Department of Horticultural Sciences, Texas A&M University, 1500 Research Parkway, Suite A120, College Station, TX 77843, USA.
Texas A&M University · US

Funding

U.S. Department of Agriculture 2017-51181-26834
6 · The paper itself

Abstract

Diabetes mellitus is a chronic disease and one of the fastest-growing health challenges of the last decades. Studies have shown that chronic low-grade inflammation and activation of the innate immune system are intimately involved in type 2 diabetes pathogenesis.

Indexed as

Computer Simulationalpha-Amylasesalpha-GlucosidasesAnimalsAnti-Inflammatory AgentsBiological AssayCarbon-13 Magnetic Resonance SpectroscopyFruitGlycosidesHypoglycemic AgentsLigandsMiceMolecular ConformationMolecular Docking SimulationMomordica charantiaProton Magnetic Resonance Spectroscopyalpha-Amylasesalpha-GlucosidasesAnti-Inflammatory AgentscucurbitaneGlycosidesHypoglycemic AgentsLigandsRNA, MessengerTriterpenesanti-inflammatory activitycharantoside XVcucurbitane-type triterpene glycosidesin silico studyMomordica charantiaα-amylaseα-glucosidase

Identifiers

PMID33669312
PMCPMC7920048
OpenAlexW3130282652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.