Evidence map›Paper›PMID 33669107›Full record

ArticleCurrent oncology (Toronto, Ont.)2021

Higher Efficiency of Percutaneous Microwave (MWA) Than Radiofrequency Ablation (RFA) in Achieving Complete Response in Cirrhotic Patients with Early Hepatocellular Carcinoma.

Silvia Gaia, Michela Ciruolo, Davide Giuseppe Ribaldone, Emanuela Rolle, Enrica Migliore, Elena Mosso, Simone Vola, Alessandra Risso, Sharmila Fagoonee, Giorgio Maria Saracco and 1 more

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Silvia GaiaGastroenterology and Hepatology Unit, Città della Salute e della Scienza University-Hospital, 10126 Turin, Italy.
Michela CiruoloGastroenterology and Hepatology Unit, Città della Salute e della Scienza University-Hospital, 10126 Turin, Italy.
Davide Giuseppe RibaldoneDepartment of Medical Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-9421-3087
Emanuela RolleGastroenterology and Hepatology Unit, Città della Salute e della Scienza University-Hospital, 10126 Turin, Italy.
Enrica MiglioreUnit of Cancer Epidemiology, Città della Salute e della Scienza University-Hospital and Center for Cancer Prevention (CPO), 10126 Turin, Italy.
Elena MossoGastroenterology and Hepatology Unit, Città della Salute e della Scienza University-Hospital, 10126 Turin, Italy.
Simone VolaGastroenterology and Hepatology Unit, Città della Salute e della Scienza University-Hospital, 10126 Turin, Italy.
Alessandra RissoGastroenterology and Hepatology Unit, Città della Salute e della Scienza University-Hospital, 10126 Turin, Italy.
Sharmila FagooneeInstitute for Biostructure and Bioimaging (CNR) at Molecular Biotechnology Center, 10126 Turin, Italy.ORCID 0000-0001-6070-6716
Giorgio Maria SaraccoGastroenterology and Hepatology Unit, Città della Salute e della Scienza University-Hospital, 10126 Turin, Italy.ORCID 0000-0001-5310-4143
Patrizia CarucciGastroenterology and Hepatology Unit, Città della Salute e della Scienza University-Hospital, 10126 Turin, Italy.
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITPiedmont Reference Center for Epidemiology and Cancer Prevention · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundContrasting data are available in the literature regarding the superiority of percutaneous microwave ablation (MWA) or radiofrequency ablation (RFA) in very early or early (BCLA 0 or A) hepatocellular carcinoma (HCC).

aimsThe primary outcome was to compare the efficacy of RFA and MWA in achieving complete response in cirrhotic patients with early and very early HCC. The secondary outcomes were to evaluate the overall survival and the recurrence rate.

methodsA retrospective, observational, single-center study was performed. Inclusion criteria were liver cirrhosis, new diagnosis of a single node of HCC measuring a maximum of 50 mm or up to three nodules with diameter up to 35 mm, treatment with RFA or MWA. Radiological response was evaluated with multiphasic contrast-enhanced Computed Tomography or Magnetic Resonance Imaging at 5-7 weeks after thermal ablation. Complete response was defined when no vital tissue was detected after treatment.

resultsOverall, 251 HCC patients were included in this study; 81 patients were treated with MWA and 170 with RFA. The complete response rate was similar in MWA and RFA groups (out of 331 nodules, 87.5% (91/104) were treated with MWA and 84.2% (186/221) were treated with RFA,

conclusionThis study showed that MWA is more efficient than RFA in achieving complete response in HCC nodules with 21 to 35 mm diameter.

Indexed as

Carcinoma, HepatocellularCatheter AblationLiver NeoplasmsRadiofrequency AblationHumansLiver CirrhosisMicrowavesNeoplasm Recurrence, LocalRetrospective StudiesTreatment Outcomehepatocellular carcinomalocoregional therapymicrowave ablationnecrosispercutaneous techniquesradiofrequency ablationsurvival

Identifiers

PMID33669107
PMCPMC8025753
OpenAlexW3129392198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.