Evidence map›Paper›PMID 33668860›Full record

ArticleInternational journal of molecular sciences2021

Aromadendrin Protects Neuronal Cells from Methamphetamine-Induced Neurotoxicity by Regulating Endoplasmic Reticulum Stress and PI3K/Akt/mTOR Signaling Pathway.

Hyun-Su Lee, Eun-Nam Kim, Gil-Saeng Jeong

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Gene editing of authenticHorticulture research · 2023
    Article
  8. Review
  9. BioMed research international · 2023
    Article
  10. mTOR Signaling Network in Cell Biology and Human Disease.International journal of molecular sciences · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hyun-Su LeeCollege of Pharmacy, Keimyung University, Daegu 42601, Korea.
Eun-Nam KimCollege of Pharmacy, Keimyung University, Daegu 42601, Korea.
Gil-Saeng JeongCollege of Pharmacy, Keimyung University, Daegu 42601, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methamphetamine (METH) is a highly addictive drug that induces irreversible damage to neuronal cells and pathological malfunction in the brain. Aromadendrin, isolated from the flowers of

Indexed as

ApoptosisAutophagyCell DeathCell Line, TumorEndoplasmic Reticulum StressFlavonoidsHumansMethamphetamineNeuronsNeuroprotective AgentsNeurotoxinsPhosphatidylinositol 3-KinasePhosphorylationProto-Oncogene Proteins c-aktSignal TransductionSirolimusaromadedrinFlavonoidsMethamphetamineNeuroprotective AgentsNeurotoxinsPhosphatidylinositol 3-KinaseProto-Oncogene Proteins c-aktSirolimusTOR Serine-Threonine KinasesaromadendrinMETHmTOR signalingneurotoxicityprotectionSH-SY5y cells

Identifiers

PMID33668860
PMCPMC7956189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.