Evidence map›Paper›PMID 33668723›Full record

ArticleInternational journal of molecular sciences2021

Identification of Enzymatic Bottlenecks for the Aerobic Production of Malate from Glycerol by the Systematic Gene Overexpression of Anaplerotic Enzymes in

Zamira E Soto-Varela, Gema Cabrera, Agustin Romero, Domingo Cantero, Antonio Valle, Jorge Bolivar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Cofactor Metabolic Engineering ofBioengineering (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Zamira E Soto-VarelaDepartment of Biomedicine, Biotechnology and Public Health-Biochemistry and Molecular Biology, Campus Universitario de Puerto Real, University of Cadiz, 11510 Puerto Real, Spain.
Gema CabreraDepartment of Chemical Engineering and Food Technology, Campus Universitario de Puerto Real, University of Cadiz, 11510 Puerto Real, Spain.ORCID 0000-0002-0196-6443
Agustin RomeroDepartment of Biomedicine, Biotechnology and Public Health-Biochemistry and Molecular Biology, Campus Universitario de Puerto Real, University of Cadiz, 11510 Puerto Real, Spain.
Domingo CanteroDepartment of Chemical Engineering and Food Technology, Campus Universitario de Puerto Real, University of Cadiz, 11510 Puerto Real, Spain.ORCID 0000-0002-1643-2831
Antonio ValleDepartment of Biomedicine, Biotechnology and Public Health-Biochemistry and Molecular Biology, Campus Universitario de Puerto Real, University of Cadiz, 11510 Puerto Real, Spain.ORCID 0000-0002-4459-4627
Jorge BolivarDepartment of Biomedicine, Biotechnology and Public Health-Biochemistry and Molecular Biology, Campus Universitario de Puerto Real, University of Cadiz, 11510 Puerto Real, Spain.ORCID 0000-0002-2645-9528
Universidad de Cádiz · ES

Funding

Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía D.P12-TEP-725Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía PAIDI GROUP CTS-569Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía PAIDI GROUP TEP-105
6 · The paper itself

Abstract

The biotechnological production of dicarboxylic acids (C4) from renewable carbon sources represents an attractive approach for the provision of these valuable compounds by green chemistry means. Glycerol has become a waste product of the biodiesel industry that serves as a highly reduced carbon source for some microorganisms.

Indexed as

Gene Expression Regulation, BacterialAerobiosisBicarbonatesEscherichia coliGlycerolKineticsMalate DehydrogenaseMalatesMutationPhosphoenolpyruvate CarboxylaseBicarbonatesGlycerolMalate DehydrogenaseMalatesmalic acidPhosphoenolpyruvate Carboxylaseanaplerotic enzymesbicarbonateC4 compoundsEscherichia coliglycerolmalatePcksuccinateTCA cycle

Identifiers

PMID33668723
PMCPMC7956688
OpenAlexW3131843906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.