Evidence map›Paper›PMID 33668699›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Effects of Red and White Ginseng Preparations on Electrical Activity of the Brain in Elderly Subjects: A Randomized, Double-Blind, Placebo-Controlled, Three-Armed Cross-Over Study.

Wilfried Dimpfel, Pierre-Antoine Mariage, Alexander G Panossian

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Wilfried DimpfelDepartmrent of Pharmacology, Justus-Liebig-University Giessen, Germany c/o A 4164 Schwarzenberg am Böhmerwald, Panoramaweg 21, Schwarzenberg am Böhmerwald, Övre-Österrike, 4164 Österrike, Austria.
Pierre-Antoine MariageBotalys SA, 8 Quai des Usines, 7800 Ath, Belgium.
Alexander G PanossianDepartment of Research & Development, Phytomed AB, Bofinkvagen 1, 31275 Vaxtorp, Sweden.ORCID 0000-0002-8467-4525
Justus-Liebig-Universität Gießen · DE

Funding

Botalys SA 2019-02Europharma USA 2019-2
6 · The paper itself

Abstract

backgroundRecently, the superior efficacy of hydroponically cultivated red ginseng preparation HRG80

methodsChanges in the electroencephalogram (EEG) frequency ranges of 17 different brain regions were measured after single and repeated administration of HRG80

resultsBoth red and white ginseng preparations had a strong impact on brain activity, with different effects on various brain regions depending on the mental load during relaxation and cognitive tasks associated with memory, attention, and mental performance. Both ginseng preparations exhibited significant effects on spectral powers compared to placebo, reflecting an activating action. The spectral changes in the quantitative EEG induced by HRG80

conclusionThe results of this study suggest that both hydroponically cultivated red and wild growing white ginseng have similar beneficial effects on the cognitive functions of elderly subjects, as reflected by electric brain activity, but their modes of action on the brain are different.

Indexed as

braincognitiondiscriminant analysiselderly subjectsPanax ginsengquantitative EEG

Identifiers

PMID33668699
PMCPMC7996201
OpenAlexW3130047156

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.