ReviewJournal of clinical medicine2021
Transanal Irrigation for Neurogenic Bowel Disease, Low Anterior Resection Syndrome, Faecal Incontinence and Chronic Constipation: A Systematic Review.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 5 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Transanal irrigation: Bridging the gap in treatment for chronic constipation and/or faecal incontinence-A systematic review and management guidance.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Pooled it
- Transanal irrigation is effective for low anterior resection syndrome: a systematic review and meta-analysis of randomized controlled trials.Techniques in coloproctology · 2025Pooled it
- Therapeutic strategies for low anterior resection syndrome: an umbrella review of systematic reviews.International journal of colorectal disease · 2025Pooled it
- The efficacy of retrograde and antegrade enemas in the management of low anterior resection syndrome in patients undergoing rectal resection: a systematic review and meta-analysis.BMC gastroenterology · 2025Pooled it
- Consensus-driven protocol for transanal irrigation in patients with low anterior resection syndrome and functional constipation.Techniques in coloproctology · 2024Guideline
- Early transanal irrigation in spinal cord injury-related neurogenic bowel dysfunction: preliminary insights.Spinal cord series and cases · 2026Trial
- Neurogenic gastrointestinal, urinary, and sexual dysfunction in multiple sclerosis: a multidisciplinary framework for clinical practice.The Lancet regional health. Europe · 2026Review
- Transanal irrigation in clinical practice: a scoping review.International journal of colorectal disease · 2026Article
- Expert recommendations for the management of fecal incontinence in systemic sclerosis: A report from the World Scleroderma Foundation (WSF) Gastrointestinal "Ad hoc committee".Journal of scleroderma and related disorders · 2026Article
- Bowel perforation following transanal irrigation in low anterior resection syndrome.Journal of surgical case reports · 2025Article
- Enhancing bowel health and hygiene with portable toilet sprayers for low- and middle-income countries.Annals of medicine and surgery (2012) · 2025Article
- Article
- Management of Fecal Incontinence: Etiology, Diagnostic Approach, and Conservative Therapy.Visceral medicine · 2024Review
- Long-term outcome of transanal irrigation for individuals with spina bifida: a 12-year experience study.Techniques in coloproctology · 2024Article
- Application of pelvic floor rehabilitation in patients with colorectal cancer: a scoping review.Techniques in coloproctology · 2024Article
- Article
- The Functional Implications of Transanal Irrigation: Insights from Pathophysiology and Clinical Studies of Neurogenic Bowel Dysfunction.Journal of clinical medicine · 2024Review
- Faecal incontinence-a comprehensive review.Frontiers in surgery · 2024Review
- Intermittent colonic exoperistalsis for chronic constipation in spinal cord-injured individuals. A long-term structured patient feedback survey to evaluate home care use.Spinal cord series and cases · 2023Article
- Transanal irrigation in functional bowel disorders and LARS: short-term results from an Italian national study.Techniques in coloproctology · 2023Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transanal irrigation (TAI) has received increasing attention as a treatment option in patients with bowel dysfunction. This systematic review was conducted according to the PRISMA guidelines and evaluates the effect of TAI in neurogenic bowel dysfunction (NBD), low anterior resection syndrome (LARS), faecal incontinence (FI) and chronic constipation (CC). The primary outcome was the effect of TAI on bowel function. Secondary outcomes included details on TAI, quality of life (QoL), the discontinuation rate, adverse events, predictive factors for a successful outcome, and health economics. A systematic search for articles reporting original data on the effect of TAI on bowel function was performed, and 27 eligible studies including 1435 individuals were included. Three randomised controlled trials, one non-randomised trial, and 23 observational studies were included; 70% of the studies were assessed to be of excellent or good methodological quality. Results showed an improvement in bowel function among patients with NBD, LARS, FI, and CC with some studies showing improvement in QoL. However, discontinuation rates were high. Side effects were common, but equally prevalent among comparative treatments. No consistent predictive factors for a successful outcome were identified. Results from this review show that TAI improves bowel function and potentially QoL; however, evidence remains limited.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.