Evidence map›Paper›PMID 33668649›Full record

ReviewInternational journal of molecular sciences2021

Prokaryotic Solute/Sodium Symporters: Versatile Functions and Mechanisms of a Transporter Family.

Tania Henriquez, Larissa Wirtz, Dan Su, Heinrich Jung

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 36 citations in OpenAlex.

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  14. The polyextremophileApplied and environmental microbiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tania HenriquezMicrobiology, Department Biology 1, Ludwig Maximilians University Munich, D-82152 Martinsried, Germany.ORCID 0000-0003-0543-9250
Larissa WirtzMicrobiology, Department Biology 1, Ludwig Maximilians University Munich, D-82152 Martinsried, Germany.ORCID 0000-0002-5334-6684
Dan SuMicrobiology, Department Biology 1, Ludwig Maximilians University Munich, D-82152 Martinsried, Germany.ORCID 0000-0002-2435-5450
Heinrich JungMicrobiology, Department Biology 1, Ludwig Maximilians University Munich, D-82152 Martinsried, Germany.ORCID 0000-0002-5450-3063
Ludwig-Maximilians-Universität München · DE

Funding

Deutsche Forschungsgemeinschaft JU333/5-1, 2 (SPP1617)Deutsche Forschungsgemeinschaft JU333/6-1
6 · The paper itself

Abstract

The solute/sodium symporter family (SSS family; TC 2.A.21; SLC5) consists of integral membrane proteins that use an existing sodium gradient to drive the uphill transport of various solutes, such as sugars, amino acids, vitamins, or ions across the membrane. This large family has representatives in all three kingdoms of life. The human sodium/iodide symporter (NIS) and the sodium/glucose transporter (SGLT1) are involved in diseases such as iodide transport defect or glucose-galactose malabsorption. Moreover, the bacterial sodium/proline symporter PutP and the sodium/sialic acid symporter SiaT play important roles in bacteria-host interactions. This review focuses on the physiological significance and structural and functional features of prokaryotic members of the SSS family. Special emphasis will be given to the roles and properties of proteins containing an SSS family domain fused to domains typically found in bacterial sensor kinases.

Indexed as

Bacterial Physiological PhenomenaHost-Pathogen InteractionsAmino Acid Transport Systems, NeutralBacteriaBacterial ProteinsHumansSodium-Glucose Transporter 1Sodium-Iodide SymportersSymportersAmino Acid Transport Systems, NeutralBacterial ProteinsSLC5A1 protein, humanSodium-Glucose Transporter 1Sodium-Iodide SymportersSymportersbacterial sensor kinasebacterial two-component systemsPutPsecondary transportsignal transductionSLC5solute/sodium symport

Identifiers

PMID33668649
PMCPMC7918813
OpenAlexW3129730415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.