Evidence map›Paper›PMID 33668512›Full record

ArticleMicromachines2021

Micromotor Manipulation Using Ultrasonic Active Traveling Waves.

Hiep Xuan Cao, Daewon Jung, Han-Sol Lee, Gwangjun Go, Minghui Nan, Eunpyo Choi, Chang-Sei Kim, Jong-Oh Park, Byungjeon Kang

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Acoustics-Actuated Microrobots.Micromachines · 2022
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Hiep Xuan CaoKorea Institute of Medical Microrobotics, Gwangju 506813, Korea.ORCID 0000-0002-0623-4807
Daewon JungKorea Institute of Medical Microrobotics, Gwangju 506813, Korea.
Han-Sol LeeKorea Institute of Medical Microrobotics, Gwangju 506813, Korea.ORCID 0000-0002-8715-3274
Gwangjun GoKorea Institute of Medical Microrobotics, Gwangju 506813, Korea.
Minghui NanKorea Institute of Medical Microrobotics, Gwangju 506813, Korea.
Eunpyo ChoiKorea Institute of Medical Microrobotics, Gwangju 506813, Korea.
Chang-Sei KimKorea Institute of Medical Microrobotics, Gwangju 506813, Korea.ORCID 0000-0003-4532-2006
Jong-Oh ParkKorea Institute of Medical Microrobotics, Gwangju 506813, Korea.
Byungjeon KangKorea Institute of Medical Microrobotics, Gwangju 506813, Korea.ORCID 0000-0003-1185-1911
Chonnam National University · KR

Funding

Korea Health Industry Development Institute HI19C0642
6 · The paper itself

Abstract

The ability to manipulate therapeutic agents in fluids is of interest to improve the efficiency of targeted drug delivery. Ultrasonic manipulation has great potential in the field of therapeutic applications as it can trap and manipulate micro-scale objects. Recently, several methods of ultrasonic manipulation have been studied through standing wave, traveling wave, and acoustic streaming. Among them, the traveling wave based ultrasonic manipulation is showing more advantage for in vivo environments. In this paper, we present a novel ultrasonic transducer (UT) array with a hemispherical arrangement that generates active traveling waves with phase modulation to manipulate a micromotor in water. The feasibility of the method could be demonstrated by in vitro and ex vivo experiments conducted using a UT array with 16 transducers operating at 1 MHz. The phase of each transducer was controlled independently for generating a twin trap and manipulation of a micromotor in 3D space. This study shows that the ultrasonic manipulation device using active traveling waves is a versatile tool that can be used for precise manipulation of a micromotor inserted in a human body and targeted for drug delivery.

Indexed as

acoustic manipulationactive traveling wavenon-contact manipulationparticle manipulationtargeted drug deliveryultrasonic actuation

Identifiers

PMID33668512
PMCPMC7918005
OpenAlexW3132292489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.