Evidence map›Paper›PMID 33668468›Full record

ArticleMolecules (Basel, Switzerland)2021

Novel Inhibitors of Nicotinamide-

Aimo Kannt, Sridharan Rajagopal, Mahanandeesha S Hallur, Indu Swamy, Rajendra Kristam, Saravanakumar Dhakshinamoorthy, Joerg Czech, Gernot Zech, Herman Schreuder, Sven Ruf

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. The Role of NADPharmaceuticals (Basel, Switzerland) · 2024
    Review
  4. NADAntioxidants (Basel, Switzerland) · 2023
    Review
  5. Article
  6. NicotinamideBiomolecules · 2022
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. NicotinamideBiomolecules · 2021
    Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aimo KanntFraunhofer Institute for Translational Medicine and Pharmacology-ITMP, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany.ORCID 0000-0002-5197-2286
Sridharan RajagopalJubilant Biosys Limited, #96, Industrial Suburb, 2nd Stage Yeshwanthpur, Bangalore 560022, India.
Mahanandeesha S HallurJubilant Biosys Limited, #96, Industrial Suburb, 2nd Stage Yeshwanthpur, Bangalore 560022, India.
Indu SwamyJubilant Biosys Limited, #96, Industrial Suburb, 2nd Stage Yeshwanthpur, Bangalore 560022, India.
Rajendra KristamJubilant Biosys Limited, #96, Industrial Suburb, 2nd Stage Yeshwanthpur, Bangalore 560022, India.
Saravanakumar DhakshinamoorthyJubilant Biosys Limited, #96, Industrial Suburb, 2nd Stage Yeshwanthpur, Bangalore 560022, India.
Joerg CzechSanofi-Aventis Deutschland Gmbh, Industriepark Hoechst, 65926 Frankfurt am Main, Germany.
Gernot ZechSanofi-Aventis Deutschland Gmbh, Industriepark Hoechst, 65926 Frankfurt am Main, Germany.
Herman SchreuderSanofi-Aventis Deutschland Gmbh, Industriepark Hoechst, 65926 Frankfurt am Main, Germany.ORCID 0000-0003-2249-2782
Sven RufSanofi-Aventis Deutschland Gmbh, Industriepark Hoechst, 65926 Frankfurt am Main, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotinamide-

Indexed as

AnimalsBinding SitesEnzyme InhibitorsHigh-Throughput Screening AssaysHumansLigandsMetabolic DiseasesMiceMicrosomes, LiverModels, MolecularNiacinamideNicotinamide N-MethyltransferaseRatsSubstrate SpecificityEnzyme InhibitorsLigandsNiacinamideNicotinamide N-Methyltransferasemetabolic diseasenicotinamidenicotinamide-N-methyltransferasesmall molecule inhibitorX-ray

Identifiers

PMID33668468
PMCPMC7918612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.