Evidence map›Paper›PMID 33668466›Full record

ReviewMolecules (Basel, Switzerland)2021

Strategies for Enhancing Polyester-Based Materials for Bone Fixation Applications.

Raasti Naseem, Charalampos Tzivelekis, Matthew J German, Piergiorgio Gentile, Ana M Ferreira, Kenny Dalgarno

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Journal of tissue engineering and regenerative medicine · 2023
    Article
  11. Poly(3-hydroxybutyrate-Polymers · 2022
    Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Raasti NaseemSchool of Engineering, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.ORCID 0000-0003-1978-4370
Charalampos TzivelekisSchool of Dental Sciences, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.
Matthew J GermanSchool of Dental Sciences, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.ORCID 0000-0002-3910-6377
Piergiorgio GentileSchool of Engineering, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.
Ana M FerreiraSchool of Engineering, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.ORCID 0000-0002-7728-1619
Kenny DalgarnoSchool of Engineering, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.ORCID 0000-0003-4522-8044

Funding

Horizon 2020 814410Medical Research Council MC_PC_18057
6 · The paper itself

Abstract

Polyester-based materials are established options, regarding the manufacturing of bone fixation devices and devices in routine clinical use. This paper reviews the approaches researchers have taken to develop these materials to improve their mechanical and biological performances. Polymer blending, copolymerisation, and the use of particulates and fibre bioceramic materials to make composite materials and surface modifications have all been studied. Polymer blending, copolymerisation, and particulate composite approaches have been adopted commercially, with the primary focus on influencing the in vivo degradation rate. There are emerging opportunities in novel polymer blends and nanoscale particulate systems, to tune bulk properties, and, in terms of surface functionalisation, to optimise the initial interaction of devices with the implanted environment, offering the potential to improve the clinical performances of fracture fixation devices.

Indexed as

Orthopedic Fixation DevicesBiocompatible MaterialsBone and BonesPolyestersSurface PropertiesBiocompatible MaterialsPolyestersbiodegradable materialsbiomaterialsbone regenerationcompositescopolymersglass fibresmechanical propertiespolyesterspolymer blends

Identifiers

PMID33668466
PMCPMC7917714

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.