Evidence map›Paper›PMID 33668460›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Pharyngeal Pumping and Tissue-Specific Transgenic P-Glycoprotein Expression Influence Macrocyclic Lactone Susceptibility in

Alexander P Gerhard, Jürgen Krücken, Cedric Neveu, Claude L Charvet, Abdallah Harmache, Georg von Samson-Himmelstjerna

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. P-glycoproteins and amphids: a two-stage trajectory of ivermectin resistance in Caenorhabditis elegans.International journal for parasitology. Drugs and drug resistance · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Diethylcarbamazine, TRP channels and CaScientific reports · 2022
    Article
  8. Article
  9. Review
  10. Transgenic Expression ofInternational journal of molecular sciences · 2022
    Article
  11. Article
  12. Susceptibility ofFrontiers in pharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Alexander P GerhardInstitute for Parasitology and Tropical Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, Germany.ORCID 0000-0002-5324-3415
Jürgen KrückenInstitute for Parasitology and Tropical Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, Germany.ORCID 0000-0002-2842-8100
Cedric NeveuINRAE, Université de Tours, ISP, F-37380 Nouzilly, France.
Claude L CharvetINRAE, Université de Tours, ISP, F-37380 Nouzilly, France.ORCID 0000-0002-0596-6598
Abdallah HarmacheINRAE, Université de Tours, ISP, F-37380 Nouzilly, France.ORCID 0000-0002-7377-7641
Georg von Samson-HimmelstjernaInstitute for Parasitology and Tropical Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, Germany.
Freie Universität Berlin · DEUniversité de Tours · FR

Funding

Burroughs-Wellcome Fund Collaborative Research Travel AwardDeutsche Forschungsgemeinschaft 111144555Deutsche Forschungsgemeinschaft 251133687/GRK 2046Deutscher Akademischer Austauschdienst 5739054Hubert Curien Partnerships Program 40582SMKarl-Enigk Foundation S0229/10019/19
6 · The paper itself

Abstract

Macrocyclic lactones (MLs) are widely used drugs to treat and prevent parasitic nematode infections. In many nematode species including a major pathogen of foals,

Indexed as

Caenorhabditis elegansdrug resistancemacrocyclic lactonesnematodeparasitologyP-glycoprotein

Identifiers

PMID33668460
PMCPMC7917992
OpenAlexW3131967438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.