Evidence map›Paper›PMID 33668456›Full record

ArticleBrain sciences2021

Long-Lasting Cognitive Abnormalities after COVID-19.

Roberta Ferrucci, Michelangelo Dini, Elisabetta Groppo, Chiara Rosci, Maria Rita Reitano, Francesca Bai, Barbara Poletti, Agostino Brugnera, Vincenzo Silani, Antonella D'Arminio Monforte and 1 more

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 9 pooled it
19.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 9 syntheses or guidelines pooled it, 202 citations in OpenAlex.

  1. Pooled it
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  4. Neurocognitive Impairment in Long COVID: A Systematic Review.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025
    Pooled it
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  7. COVID-19 associated cognitive impairment: A systematic review.Cortex; a journal devoted to the study of the nervous system and behavior · 2022
    Pooled it
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  17. How do fatigue, cognitive dysfunction, activity and role functioning, and mental health inter-relate in adults with post-COVID-19 syndrome? A structural equation model analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Roberta FerrucciAldo Ravelli Research Center for Neurotechnology and Experimental Brain Therapeutics, University of Milan, 20142 Milan, Italy.ORCID 0000-0001-5109-9483
Michelangelo DiniAldo Ravelli Research Center for Neurotechnology and Experimental Brain Therapeutics, University of Milan, 20142 Milan, Italy.ORCID 0000-0002-2430-8902
Elisabetta GroppoASST-Santi Paolo e Carlo University Hospital, 20142 Milan, Italy.
Chiara RosciASST-Santi Paolo e Carlo University Hospital, 20142 Milan, Italy.
Maria Rita ReitanoASST-Santi Paolo e Carlo University Hospital, 20142 Milan, Italy.
Francesca BaiASST-Santi Paolo e Carlo University Hospital, 20142 Milan, Italy.
Barbara PolettiDepartment of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italian, 20149 Milan, Italy.
Agostino BrugneraDepartment of Human and Social sciences, University of Bergamo, 24129 Bergamo, Italy.ORCID 0000-0002-4066-4552
Vincenzo SilaniAldo Ravelli Research Center for Neurotechnology and Experimental Brain Therapeutics, University of Milan, 20142 Milan, Italy.ORCID 0000-0002-7698-3854
Antonella D'Arminio MonforteASST-Santi Paolo e Carlo University Hospital, 20142 Milan, Italy.
Alberto PrioriAldo Ravelli Research Center for Neurotechnology and Experimental Brain Therapeutics, University of Milan, 20142 Milan, Italy.
University of Milan · ITIRCCS Istituto Auxologico Italiano · ITUniversity of Bergamo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Considering the mechanisms capable of causing brain alterations in COVID-19, we aimed to study the occurrence of cognitive abnormalities in the months following hospital discharge. We recruited 38 (aged 22-74 years; 27 males) patients hospitalized for complications of SARS-CoV-2 infection in nonintensive COVID units. Participants underwent neuropsychological testing about 5 months after hospital discharge. Of all patients, 42.1% had processing speed deficits, while 26.3% showed delayed verbal recall deficits. Twenty-one percent presented with deficits in both processing speed and verbal memory. Bivariate analysis revealed a positive correlation between the lowest arterial oxygen partial pressure (PaO

Indexed as

acute respiratory distress syndromecognitionCOVID-19processing speed

Identifiers

PMID33668456
PMCPMC7917789
OpenAlexW3130589665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.