Evidence map›Paper›PMID 33668391›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Dietary Antioxidant Vitamins and Minerals and Breast Cancer Risk: Prospective Results from the SUN Cohort.

Cesar I Fernandez-Lazaro, Miguel Ángel Martínez-González, Inmaculada Aguilera-Buenosvinos, Alfredo Gea, Miguel Ruiz-Canela, Andrea Romanos-Nanclares, Estefanía Toledo

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Cesar I Fernandez-LazaroDepartment of Preventive Medicine and Public Health, University of Navarra, 31008 Pamplona, Spain.
Miguel Ángel Martínez-GonzálezDepartment of Preventive Medicine and Public Health, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-3917-9808
Inmaculada Aguilera-BuenosvinosDepartment of Preventive Medicine and Public Health, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-9484-7303
Alfredo GeaDepartment of Preventive Medicine and Public Health, University of Navarra, 31008 Pamplona, Spain.
Miguel Ruiz-CanelaDepartment of Preventive Medicine and Public Health, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-7684-2787
Andrea Romanos-NanclaresDepartment of Preventive Medicine and Public Health, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-9694-7607
Estefanía ToledoDepartment of Preventive Medicine and Public Health, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-6263-4434
Instituto de Salud Carlos III · ESNavarre Institute of Health Research · ESHarvard University · US

Funding

European Regional Development Fund RD 06/0045Gobierno de Navarra 27/2011, 45/2011, 122/2014Instituto de Salud Carlos III PI10/02658, PI10/02293, PI13/00615, PI14/01668, PI14/01798, PI14/01764, PI17/01795, and G03/140Universidad de Navarra -
6 · The paper itself

Abstract

There is growing interest in natural antioxidants and their potential effects on breast cancer (BC). Epidemiological evidence, however, is inconsistent. We prospectively evaluated the association between dietary intake of vitamins A, C, and E, selenium, and zinc and BC among 9983 female participants from the SUN Project, a Mediterranean cohort of university graduates. Participants completed a food frequency questionnaire at baseline, and biennial follow-up information about incident BC diagnosis was collected. Cases were ascertained through revision of medical charts and consultation of the National Death Index. Cox proportional hazards models were used to estimate multivariable-adjusted hazard ratios (HRs) and 95% confidence intervals (CI). During an average follow-up of 11.3 years, 107 incident BC cases were confirmed. The multivariable HRs (95% CI) for BC comparing extreme tertiles of energy-adjusted dietary intakes were 1.07 (0.64-1.77;

Indexed as

antioxidantsbreast cancerMediterranean populationseleniumSUN cohortvitamin Avitamin Cvitamin Ezinc

Identifiers

PMID33668391
PMCPMC7996327
OpenAlexW3133232367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.