Evidence map›Paper›PMID 33668311›Full record

ReviewSensors (Basel, Switzerland)2021

Near-Infrared Spectroscopy (NIRS) in Traumatic Brain Injury (TBI).

María Roldán, Panayiotis A Kyriacou

3 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05632302 nacompletednot on this map

A Pilot Study to Estimate Intracranial Pressure Noninvasively in Traumatic Brain Injury Patients

TypeinterventionalSponsorCrainio LtdaRan2020 to 2021Enrolled40ConditionsTraumatic Brain Injury, Intracranial HypertensionArmsnICP
NCT06306950 nacompletednot on this map

Optimization of Cerebral Oximetry And Avoid Cerebral Deoxygenation In Severe Traumatic Brain Injury.

TypeinterventionalSponsorPhramongkutklao College of Medicine and HospitalRan2021 to 2024Enrolled80ConditionsCerebral Hypoxia, Severe Traumatic Brain InjuryArmsNear infrared spectroscopy neuromonitor to prevent cerebral desaturation
NCT06453733 narecruitingnot on this mapstarted 2025, after this paper: background citation

Crainio Non-invasive Intracranial Pressure Monitor for Traumatic Brain Injury: Product Development

TypeinterventionalSponsorCrainio LtdaRan2025 to 2026Enrolled54ConditionsTraumatic Brain InjuryArmsCrainio
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 75 citations in OpenAlex.

  1. Trial
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  8. Non-Invasive Measurement of Brain Temperature using Microwave Radiothermometry.Bulletin of experimental biology and medicine · 2026
    Article
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  11. Review
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  17. Brain health: A concern for anaesthesiologists and intensivists.European journal of anaesthesiology and intensive care · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

María RoldánResearch Centre for Biomedical Engineering, School of Mathematics, Computer Sciences and Engineering, University of London, London EC1V 0HB, UK.ORCID 0000-0002-7298-813X
Panayiotis A KyriacouResearch Centre for Biomedical Engineering, School of Mathematics, Computer Sciences and Engineering, University of London, London EC1V 0HB, UK.ORCID 0000-0002-2868-485X
City, University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traumatic brain injury (TBI) occurs when a sudden trauma causes damage to the brain. TBI can result when the head suddenly and violently impacts an object or when an object pierces the skull and enters brain tissue. Secondary injuries after traumatic brain injury (TBI) can lead to impairments on cerebral oxygenation and autoregulation. Considering that secondary brain injuries often take place within the first hours after the trauma, noninvasive monitoring might be helpful in providing early information on the brain's condition. Near-infrared spectroscopy (NIRS) is an emerging noninvasive monitoring modality based on chromophore absorption of infrared light with the capability of monitoring perfusion of the brain. This review investigates the main applications of NIRS in TBI monitoring and presents a thorough revision of those applications on oxygenation and autoregulation monitoring. Databases such as PubMed, EMBASE, Web of Science, Scopus, and Cochrane library were utilized in identifying 72 publications spanning between 1977 and 2020 which were directly relevant to this review. The majority of the evidence found used NIRS for diagnosis applications, especially in oxygenation and autoregulation monitoring (59%). It was not surprising that nearly all the patients were male adults with severe trauma who were monitored mostly with continue wave NIRS or spatially resolved spectroscopy NIRS and an invasive monitoring device. In general, a high proportion of the assessed papers have concluded that NIRS could be a potential noninvasive technique for assessing TBI, despite the various methodological and technological limitations of NIRS.

Indexed as

Brain Injuries, TraumaticSpectroscopy, Near-InfraredAdultBrainHumansMaleMonitoring, Physiologiccerebral autoregulationcerebral oxygenationnear infrared spectroscopytraumatic brain injury

Identifiers

PMID33668311
PMCPMC7956674
OpenAlexW3133083263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.