Evidence map›Paper›PMID 33668260›Full record

ArticleSensors (Basel, Switzerland)2021

Thermal Ablation and High-Resolution Imaging Using a Back-to-Back (BTB) Dual-Mode Ultrasonic Transducer: In Vivo Results.

Hae Gyun Lim, Hyunhee Kim, Kyungmin Kim, Jeongwoo Park, Yeonggeun Kim, Jinhee Yoo, Dasom Heo, Jinhwan Baik, Sung-Min Park, Hyung Ham Kim

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Image-Based Monitoring of Thermal Ablation.Bioengineering (Basel, Switzerland) · 2025
    Review
  5. Review
  6. Design of Preamplifier for Ultrasound Transducers.Sensors (Basel, Switzerland) · 2024
    Review
  7. Therapeutic ultrasound transducer technology and monitoring techniques: a review with clinical examples.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2024
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hae Gyun LimDepartment of Biomedical Engineering, Pukyong National University, Busan 48513, Korea.ORCID 0000-0002-4182-7130
Hyunhee KimSchool of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang 37673, Korea.ORCID 0000-0003-3241-3638
Kyungmin KimDepartment of Convergence IT Engineering, Pohang University of Science and Technology, Pohang 37673, Korea.
Jeongwoo ParkSchool of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang 37673, Korea.ORCID 0000-0003-3366-2329
Yeonggeun KimDepartment of Convergence IT Engineering, Pohang University of Science and Technology, Pohang 37673, Korea.
Jinhee YooSchool of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang 37673, Korea.
Dasom HeoDepartment of Mechanical Engineering, Pohang University of Science and Technology, Pohang 37673, Korea.
Jinhwan BaikDepartment of Convergence IT Engineering, Pohang University of Science and Technology, Pohang 37673, Korea.ORCID 0000-0002-8848-6062
Sung-Min ParkDepartment of Convergence IT Engineering, Pohang University of Science and Technology, Pohang 37673, Korea.ORCID 0000-0002-8359-8110
Hyung Ham KimSchool of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang 37673, Korea.ORCID 0000-0002-6353-5550

Funding

ICT Consilience Creative program IITP-2020-2011-1-00783National Research Foundation of Korea 2018R1D1A1A02085904National Research Foundation of Korea 2019R1A2C2010484
6 · The paper itself

Abstract

We present a back-to-back (BTB) structured, dual-mode ultrasonic device that incorporates a single-element 5.3 MHz transducer for high-intensity focused ultrasound (HIFU) treatment and a single-element 20.0 MHz transducer for high-resolution ultrasound imaging. Ultrasound image-guided surgical systems have been developed for lesion monitoring to ensure that ultrasonic treatment is correctly administered at the right locations. In this study, we developed a dual-element transducer composed of two elements that share the same housing but work independently with a BTB structure, enabling a mode change between therapy and imaging via 180-degree mechanical rotation. The optic fibers were embedded in the HIFU focal region of ex vivo chicken breasts and the temperature change was measured. Images were obtained in vivo mice before and after treatment and compared to identify the treated region. We successfully acquired B-mode and C-scan images that display the hyperechoic region indicating coagulation necrosis in the HIFU-treated volume up to a depth of 10 mm. The compact BTB dual-mode ultrasonic transducer may be used for subcutaneous thermal ablation and monitoring, minimally invasive surgery, and other clinical applications, all with ultrasound only.

Indexed as

High-Intensity Focused Ultrasound AblationUltrasonicsAnimalsMiceTransducersUltrasonographyback-to-back structuredual-mode transducerhigh-frequency ultrasonic imaginghigh intensity focused ultrasound (HIFU)high-resolution imaging

Identifiers

PMID33668260
PMCPMC7956793

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.