Evidence map›Paper›PMID 33668213›Full record

ArticleInternational journal of molecular sciences2021

Construction of Boronophenylalanine-Loaded Biodegradable Periodic Mesoporous Organosilica Nanoparticles for BNCT Cancer Therapy.

Fuyuhiko Tamanoi, Shanmugavel Chinnathambi, Mathilde Laird, Aoi Komatsu, Albane Birault, Takushi Takata, Tan Le-Hoang Doan, Ngoc Xuan Dat Mai, Arthur Raitano, Kendall Morrison and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  10. UsingScientific reports · 2022
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  12. The Physical Chemistry and Chemical Physics (PCCP) Section of theInternational journal of molecular sciences · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Fuyuhiko TamanoiInstitute for Integrated Cell-Material Sciences, Institute for Advanced Study, Kyoto University, Kyoto 606-8501, Japan.ORCID 0000-0002-4220-6408
Shanmugavel ChinnathambiInstitute for Integrated Cell-Material Sciences, Institute for Advanced Study, Kyoto University, Kyoto 606-8501, Japan.ORCID 0000-0001-9550-5367
Mathilde LairdInstitute for Integrated Cell-Material Sciences, Institute for Advanced Study, Kyoto University, Kyoto 606-8501, Japan.
Aoi KomatsuInstitute for Integrated Cell-Material Sciences, Institute for Advanced Study, Kyoto University, Kyoto 606-8501, Japan.
Albane BiraultInstitute for Integrated Cell-Material Sciences, Institute for Advanced Study, Kyoto University, Kyoto 606-8501, Japan.
Takushi TakataInstitute for Integrated Radiation and Nuclear Science, Kyoto University, Kumatori, Japan.
Tan Le-Hoang DoanCenter for Innovative Materials and Architectures (INOMAR), Vietnam National University Ho Chi Minh City, Vietnam.ORCID 0000-0001-6312-9571
Ngoc Xuan Dat MaiCenter for Innovative Materials and Architectures (INOMAR), Vietnam National University Ho Chi Minh City, Vietnam.
Arthur RaitanoTAE Lifesciences, Drug Development Division, Santa Monica, CA 90404, USA.
Kendall MorrisonTAE Lifesciences, Drug Development Division, Santa Monica, CA 90404, USA.
Minoru SuzukiInstitute for Integrated Radiation and Nuclear Science, Kyoto University, Kumatori, Japan.
Kotaro MatsumotoInstitute for Integrated Cell-Material Sciences, Institute for Advanced Study, Kyoto University, Kyoto 606-8501, Japan.
Kyoto University · JPVietnam National University Ho Chi Minh City · VN

Funding

Japan Agency for Medical Research and Development 19ck016469h0001Japan Society for the Promotion of Science JP15K21764Japan Society for the Promotion of Science JP20H00331Kyoto University Kyoto University-TAE Lifesciences collaboration grantVietnam National University, HCM VNU-A-562
6 · The paper itself

Abstract

Biodegradable periodic mesoporous organosilica (BPMO) has recently emerged as a promising type of mesoporous silica-based nanoparticle for biomedical applications. Like mesoporous silica nanoparticles (MSN), BPMO possesses a large surface area where various compounds can be attached. In this work, we attached boronophenylalanine (

Indexed as

Antineoplastic AgentsApoptosisBoron CompoundsCell ProliferationHumansMetal NanoparticlesNeoplasmsOrganosilicon CompoundsPhenylalanineTumor Cells, CulturedAntineoplastic AgentsBoron CompoundsOrganosilicon CompoundsPhenylalaninebiodegradable periodic mesoporous organosilicaboron neutron capture therapyboronophenylalaninecancer cellschicken egg tumor model

Identifiers

PMID33668213
PMCPMC7956258
OpenAlexW3131850235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.