Evidence map›Paper›PMID 33668212›Full record

ArticleNutrients2021

Multiple Selection Criteria for Probiotic Strains with High Potential for Obesity Management.

Jeanne Alard, Benoit Cudennec, Denise Boutillier, Véronique Peucelle, Amandine Descat, Raphaël Decoin, Sarah Kuylle, Amin Jablaoui, Moez Rhimi, Isabelle Wolowczuk and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 37 citations in OpenAlex.

  1. Effects of Wilac D001 (Journal of microbiology and biotechnology · 2026
    Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Obesity-Related Glomerulosclerosis-How Adiposity Damages the Kidneys.International journal of molecular sciences · 2025
    Review
  11. Review
  12. Review
  13. Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Jeanne AlardU1019-UMR 9017-CIIL-Centre d'Infection et d'Immunité de Lille, Institut Pasteur de Lille, Université de Lille, CNRS, Inserm, CHU Lille, F-59000 Lille, France.
Benoit CudennecUniversité de Lille, UMR-T 1158, BioEcoAgro, F-59000 Lille, France.ORCID 0000-0002-5505-4458
Denise BoutillierU1019-UMR 9017-CIIL-Centre d'Infection et d'Immunité de Lille, Institut Pasteur de Lille, Université de Lille, CNRS, Inserm, CHU Lille, F-59000 Lille, France.
Véronique PeucelleU1019-UMR 9017-CIIL-Centre d'Infection et d'Immunité de Lille, Institut Pasteur de Lille, Université de Lille, CNRS, Inserm, CHU Lille, F-59000 Lille, France.
Amandine DescatEA 7365-GRITA-Groupe de Recherche Sur les Formes Injectables et les Technologies Associées, Université de Lille, CHU Lille, F-59000 Lille, France.
Raphaël DecoinInstitut Pasteur de Lille, Université de Lille, Inserm, CHU Lille, U1011-EGID, F-59000 Lille, France.
Sarah KuylleGENIBIO, Le Pradas, ZI du Couserans, 09190 Lorp-Sentaraille, France.
Amin JablaouiInstitut Micalis, INRAE, AgroParisTech, Université Paris-Saclay, F-78350 Jouy-en-Josas, France.
Moez RhimiInstitut Micalis, INRAE, AgroParisTech, Université Paris-Saclay, F-78350 Jouy-en-Josas, France.ORCID 0000-0001-8067-6526
Isabelle WolowczukU1019-UMR 9017-CIIL-Centre d'Infection et d'Immunité de Lille, Institut Pasteur de Lille, Université de Lille, CNRS, Inserm, CHU Lille, F-59000 Lille, France.
Bruno PotU1019-UMR 9017-CIIL-Centre d'Infection et d'Immunité de Lille, Institut Pasteur de Lille, Université de Lille, CNRS, Inserm, CHU Lille, F-59000 Lille, France.
Anne TailleuxInstitut Pasteur de Lille, Université de Lille, Inserm, CHU Lille, U1011-EGID, F-59000 Lille, France.
Emmanuelle MaguinInstitut Micalis, INRAE, AgroParisTech, Université Paris-Saclay, F-78350 Jouy-en-Josas, France.ORCID 0000-0001-5452-3382
Sophie HolowaczPiLeJe Laboratoire, 37 Quai de Grenelle, 75015 Paris, France.
Corinne GrangetteU1019-UMR 9017-CIIL-Centre d'Infection et d'Immunité de Lille, Institut Pasteur de Lille, Université de Lille, CNRS, Inserm, CHU Lille, F-59000 Lille, France.ORCID 0000-0003-2398-448X
Centre National de la Recherche Scientifique · FRAgroParisTech · FRInserm · FRUniversité de Lille · FRLaboratoire de Génétique Cellulaire · FR

Funding

ANRT 2014/0153
6 · The paper itself

Abstract

Since alterations of the gut microbiota have been shown to play a major role in obesity, probiotics have attracted attention. Our aim was to identify probiotic candidates for the management of obesity using a combination of in vitro and in vivo approaches. We evaluated in vitro the ability of 23 strains to limit lipid accumulation in adipocytes and to enhance the secretion of satiety-promoting gut peptide in enteroendocrine cells. Following the in vitro screening, selected strains were further investigated in vivo, single, or as mixtures, using a murine model of diet-induced obesity. Strain

Indexed as

AdipocytesAnimalsBile Acids and SaltsDietDisease Models, AnimalEnteroendocrine CellsGastrointestinal HormonesGastrointestinal MicrobiomeHypothalamusLeptinMiceObesityObesity ManagementProbioticsReceptors, LeptinWeight GainBile Acids and SaltsGastrointestinal HormonesLeptinReceptors, Leptinbile acidsenteroendocrine peptidesepithelial barrierhypothalamusinflammationmicrobiotaobesityprobiotics

Identifiers

PMID33668212
PMCPMC7995962
OpenAlexW3132697312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.