Evidence map›Paper›PMID 33668124›Full record

ArticleInternational journal of molecular sciences2021

Methylselenol Produced In Vivo from Methylseleninic Acid or Dimethyl Diselenide Induces Toxic Protein Aggregation in

Marc Dauplais, Katarzyna Bierla, Coralie Maizeray, Roxane Lestini, Ryszard Lobinski, Pierre Plateau, Joanna Szpunar, Myriam Lazard

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Does atmospheric dimethyldiselenide play a role in reducing COVID-19 mortality?Gondwana research : international geoscience journal · 2023
    Article
  3. Review
  4. THE MAIN CYTOTOXIC EFFECTS OF METHYLSELENINIC ACID ON VARIOUS CANCER CELLS.International journal of molecular sciences · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Marc DauplaisLaboratoire de Biologie Structurale de la Cellule, BIOC, École Polytechnique, CNRS-UMR7654, IP Paris, 91128 Palaiseau CEDEX, France.
Katarzyna BierlaIPREM UMR5254, E2S UPPA, Institut des Sciences Analytiques et de Physico-Chimie Pour l'Environnement et les Matériaux, CNRS, Université de Pau et des Pays de l'Adour, Hélioparc, 64053 Pau, France.
Coralie MaizerayLaboratoire de Biologie Structurale de la Cellule, BIOC, École Polytechnique, CNRS-UMR7654, IP Paris, 91128 Palaiseau CEDEX, France.
Roxane LestiniLaboratoire d'Optique et Biosciences, École Polytechnique, CNRS UMR7645-INSERM U1182, IP Paris, 91128 Palaiseau CEDEX, France.ORCID 0000-0001-7377-4734
Ryszard LobinskiIPREM UMR5254, E2S UPPA, Institut des Sciences Analytiques et de Physico-Chimie Pour l'Environnement et les Matériaux, CNRS, Université de Pau et des Pays de l'Adour, Hélioparc, 64053 Pau, France.
Pierre PlateauLaboratoire de Biologie Structurale de la Cellule, BIOC, École Polytechnique, CNRS-UMR7654, IP Paris, 91128 Palaiseau CEDEX, France.
Joanna SzpunarIPREM UMR5254, E2S UPPA, Institut des Sciences Analytiques et de Physico-Chimie Pour l'Environnement et les Matériaux, CNRS, Université de Pau et des Pays de l'Adour, Hélioparc, 64053 Pau, France.ORCID 0000-0002-5644-4933
Myriam LazardLaboratoire de Biologie Structurale de la Cellule, BIOC, École Polytechnique, CNRS-UMR7654, IP Paris, 91128 Palaiseau CEDEX, France.ORCID 0000-0002-7154-1352
Centre National de la Recherche Scientifique · FRWarsaw University of Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methylselenol (MeSeH) has been suggested to be a critical metabolite for anticancer activity of selenium, although the mechanisms underlying its activity remain to be fully established. The aim of this study was to identify metabolic pathways of MeSeH in

Indexed as

Protein Aggregation, PathologicalMethanolOrganoselenium CompoundsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsdimethyldiselenidemethaneselenolMethanolmethylselenic acidOrganoselenium CompoundsSaccharomyces cerevisiae Proteinsdiselenidemethylseleninic acidmethylselenolprotein aggregationredox equilibriumSaccharomyces cerevisiae metabolismthiol/disulfide exchangetoxicity

Identifiers

PMID33668124
PMCPMC7956261
OpenAlexW3131172260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.