Evidence map›Paper›PMID 33667546›Full record

ArticleThe Journal of biological chemistry

The molecular basis of the inhibition of Ca

Lingjie Sang, Daiana C O Vieira, David T Yue, Manu Ben-Johny, Ivy E Dick

Open access · goldAbstract read
In one paragraph

Article in The Journal of biological chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Sudden Death-AssociatedbioRxiv : the preprint server for biology · 2025
    Article
  4. L-Type Voltage-Gated CaBiochemistry · 2025
    Article
  5. Inactivation of CaV1 and CaV2 channels.The Journal of general physiology · 2025
    Review
  6. Role of the CaChannels (Austin, Tex.) · 2024
    Article
  7. Opto-chemogenetic inhibition of L-type CaCell reports methods · 2024
    Article
  8. Review
  9. Review
  10. Regulation of Cardiac Cav1.2 Channels by Calmodulin.International journal of molecular sciences · 2023
    Review
  11. Calmodulin promotes a CaFEBS letters · 2022
    Article
  12. Cytosolic peptides encoding CaCommunications biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lingjie SangDepartment of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Daiana C O VieiraDepartment of Physiology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
David T YueDepartment of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Manu Ben-JohnyDepartment of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Department of Physiology and Cellular Biophysics, Columbia University, New York, New York, USA.
Ivy E DickDepartment of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland, USA. Electronic address: ied@som.umaryand.edu.
Johns Hopkins University · USUniversity of Maryland, Baltimore · US

Funding

Next-generation calcium channel modulatorsR01HL149926 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI Ivy E Dick · 2020 to 2026
$3.4M
Chemical biological dissection of Ca2+ entry through Ca2+ channelsR01NS085074 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI DICK, IVY E · 2013 to 2016
$1.3M
NHLBI NIH HHS R01 HL149926NINDS NIH HHS R01 NS085074
6 · The paper itself

Abstract

Ca

Indexed as

Ion Channel GatingMutationCalciumCalmodulinCaveolin 1Cells, CulturedHumansKineticsProtein BindingStructure-Activity RelationshipCalciumCalmodulinCAV1 protein, humanCaveolin 1calcium channelcalcium-dependent inactivation (CDI)calmodulin (CaM)fluorescence resonance energy transfer (FRET)ion channelpatch clamp

Identifiers

PMID33667546
PMCPMC8054141
OpenAlexW3135858442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.