Evidence map›Paper›PMID 33667059›Full record

ArticleACS chemical neuroscience2021

Ashley C Knight, Cassis Varlow, Tong Zi, Steven H Liang, Lee Josephson, Karl Schmidt, Shil Patel, Neil Vasdev

Open access · greenAbstract read
In one paragraph

Article in ACS chemical neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  12. Discovery of a High-Affinity Fluoromethyl Analog of [ACS pharmacology & translational science · 2023
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  15. Synthesis and Evaluation of aPharmaceuticals (Basel, Switzerland) · 2022
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  16. Article
  17. Review
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Ashley C KnightAzrieli Centre for Neuro-Radiochemistry, Brain Health Imaging Centre, Centre for Addiction and Mental Health (CAMH), Toronto, ON M5T 1R8, Canada.ORCID 0000-0003-2225-360X
Cassis VarlowAzrieli Centre for Neuro-Radiochemistry, Brain Health Imaging Centre, Centre for Addiction and Mental Health (CAMH), Toronto, ON M5T 1R8, Canada.
Tong ZiCodiak Biosciences, Cambridge, Massachusetts 02140, United States.
Steven H LiangDivision of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital and Department of Radiology, Harvard Medical School, Boston, Massachusetts 02114, United States.ORCID 0000-0003-1413-6315
Lee JosephsonDivision of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital and Department of Radiology, Harvard Medical School, Boston, Massachusetts 02114, United States.
Karl SchmidtCodiak Biosciences, Cambridge, Massachusetts 02140, United States.
Shil PatelCodiak Biosciences, Cambridge, Massachusetts 02140, United States.
Neil VasdevAzrieli Centre for Neuro-Radiochemistry, Brain Health Imaging Centre, Centre for Addiction and Mental Health (CAMH), Toronto, ON M5T 1R8, Canada.ORCID 0000-0002-2087-5125
Centre for Addiction and Mental Health · CAHarvard University · US

Funding

Translation of tau-selective PET radiopharmaceuticals in Alzheimers patientsR01AG052414 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI PRICE, JULIE C, VASDEV, NEIL · 2018 to 2021
$2.7M
Neuro-PET Radiotracer Discovery for Imaging Glycogen Synthase Kinase-3R01AG054473 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI VASDEV, NEIL · 2017 to 2020
$1.7M
NIA NIH HHS R01 AG052414NIA NIH HHS R01 AG054473
6 · The paper itself

Abstract

Microglia play a role in several central nervous system (CNS) diseases and are a highly sought target for positron emission tomography (PET) imaging and therapeutic intervention. 5-Cyano-

Indexed as

MicrogliaPositron-Emission TomographyAnimalsAutoradiographyRadiopharmaceuticalsReceptor Protein-Tyrosine KinasesRodentiaRadiopharmaceuticalsReceptor Protein-Tyrosine Kinasesautoradiographycolony stimulating factor-1 receptorCPPCCSF-1Rin vitroPETPositron emission tomography

Identifiers

PMID33667059
PMCPMC9350903
OpenAlexW3135325341

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.