Evidence map›Paper›PMID 33666898›Full record

ArticleEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2021

Is it time to reconsider the use of vital teeth bleaching in children and adolescents in Europe?

F Griffiths, S Parekh

Abstract read
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In one paragraph

Article in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

F GriffithsEastman Dental Institute, University College London, 123 Grays Inn Road, Holborn, London, WC1X 8LT, UK. Friederike.Griffiths1@nhs.net.ORCID http://orcid.org/0000-0002-3591-8968
S ParekhEastman Dental Institute, University College London, 123 Grays Inn Road, Holborn, London, WC1X 8LT, UK.
Eastman Dental Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to determine whether carbamide peroxide is effective in bleaching vital permanent teeth in children.

methodsA literature search was conducted using all keywords relevant to the research subject. The outcome measures were identified as colour change, tooth sensitivity, oral irritation and patient satisfaction. The certainty of evidence for each outcome was assessed using the current GRADE guidelines.

resultsOf 115 potentially relevant articles, 112 were excluded, as they did not exclusively involve children, intervention involved additional treatment such as microabrasion or restorative work, or case studies. Patient satisfaction was not assessed in the three articles so no analysis could be made with regards to this outcome. The GRADE assessment showed that all of the three articles demonstrated very low certainty of evidence for the other assessed outcomes. The overall findings from the studies suggest that a 10% carbamide peroxide overnight tray system is effective at bleaching vital permanent teeth in children and associated tooth sensitivity and oral irritation are found to be in a similar range compared to those reported in adult studies. However, due to the very low certainty of the evidence, it is not possible to draw these conclusions.

conclusionBetter quality randomised controlled trials are needed to investigate the indication, short and long term effectiveness and side effects of carbamide teeth in vital permanent teeth in children.

Indexed as

Dentin SensitivityTooth BleachingAdolescentAdultCarbamide PeroxideChildDrug CombinationsEuropeHumansPeroxidesCarbamide PeroxideDrug CombinationsPeroxidesAdolescentCarbamide peroxideChildEU lawTooth bleachingTooth whitening

Identifiers

PMID33666898
OpenAlexW3135822097

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.