Evidence map›Paper›PMID 33666880›Full record

ArticleEuropean geriatric medicine2021

Bidirectional relationship between depressive symptoms and physical performance in community-dwelling older people with subjective memory complaints.

Eiko Takano, Mathieu Maltais, Izumi Kondo, Yves Rolland, MAPT/DSA group

Registry-linked trialAbstract read
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In one paragraph

Article in European geriatric medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01513252 (A 2-years Extension Study of MAPT Trial), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01513252 nacompletednot on this map

A 2-years Extension Study of MAPT Trial : Evaluation of the Long Term Effects of Interventional Strategies to Prevent the Decline in Cognitive Functioning in Frail Older Adults

TypeinterventionalSponsorUniversity Hospital, ToulouseRan2011 to 2020Enrolled1,028ConditionsFrail ElderlyArmsGröber and Buschke test
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Eiko TakanoGérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Toulouse, France. eikoath@ncgg.go.jp.ORCID http://orcid.org/0000-0003-2623-0405
Mathieu MaltaisGérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Toulouse, France.ORCID http://orcid.org/0000-0001-5096-1019
Izumi KondoCenter of Assistive Robotics and Rehabilitation for Longevity and Good Health, National Center for Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi, 474-8511, Japan.ORCID http://orcid.org/0000-0002-1675-7310
Yves RollandGérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Toulouse, France.ORCID http://orcid.org/0000-0002-1157-0215
MAPT/DSA group
Centre Hospitalier Universitaire de Toulouse · FRUniversité de Sherbrooke · CAUniversité Toulouse III - Paul Sabatier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study examined the bidirectional relationship between depressive symptoms and physical performance in community-dwelling older people with subjective memory complaints.

methodsSecondary analyses using data from the Multidomain Alzheimer Preventive Trial (MAPT) study were performed. The participants were 1679 subjects (female, 64.8%; mean age, 75.3 ± 4.4 years). The outcome measures were depressive symptoms assessed by the 15-item Geriatric Depression Scale (GDS) and physical performance assessed by the Short Physical Performance Battery (SPPB) and handgrip strength (HGS). All measurements were performed at baseline and at 6, 12, 24, and 36 months. The bidirectional relationships of GDS with SPPB and HGS were examined using mixed-effect regression analysis.

resultsBaseline physical performance was significantly associated with a decreased GDS score (SPPB score: β = - 0.210, 95% confidence interval [CI], - 0.283 to - 0.137; HGS: β = - 0.038, 95% CI - 0.056 to - 0.019). The baseline GDS score was significantly associated with decreased physical performance (SPPB score: β = - 0.082, 95% CI - 0.107 to - 0.056; HGS: β = - 0.261, 95% CI - 0.370 to - 0.152).

conclusionSince depressive symptoms and physical performance had a bidirectional relationship, prevention or improvement of decreased physical performance could play a role in reducing depressive symptoms, and addressing depressive symptoms may play a role in improving physical performance. TRIAL REGISTRATION NUMBER: NCT01513252.

Indexed as

Alzheimer DiseaseDepressionAgedFemaleHand StrengthHumansIndependent LivingMalePhysical Functional PerformanceBidirectional relationshipCommunity-dwelling older peopleDepressive symptomsPhysical performanceSubjective memory complaints

Identifiers

PMID33666880
OpenAlexW3133535908

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.