ArticleMycotoxin research2021
Analysis of 13 Alternaria mycotoxins including modified forms in beer.
Article in Mycotoxin research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Bioprocessing of monomethyl ether from Alternaria alternata, a multi-target antiproliferative compound as emphasized by in silico analysis.Scientific reports · 2026Article
- Quantitation of Vitamin B6 Vitamers and Glycosides in German Alcohol-Free and Full-Strength Beer by a Stable Isotope Dilution LC-MS/MS Method.Journal of agricultural and food chemistry · 2026Article
- Prevalence and Exposure Assessment ofFoods (Basel, Switzerland) · 2025Article
- Deoxynivalenol andFoods (Basel, Switzerland) · 2025Article
- Recent Advances in the Detection of Food Toxins Using Mass Spectrometry.Chemical research in toxicology · 2023Review
- Tenuazonic acid alters immune and physiological reactions and susceptibility to pathogens in Galleria mellonella larvae.Mycotoxin research · 2023Article
- Development of analytical methods to study the effect of malting on levels of free and modified forms of Alternaria mycotoxins in barley.Mycotoxin research · 2022Article
- Screening of Mycotoxigenic Fungi in Barley and Barley Malt (Foods (Basel, Switzerland) · 2022Article
- Assessment of Human Exposure to FiveToxins · 2021Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A multi-mycotoxin LC-MS/MS method was developed to quantify 13 free and modified Alternaria toxins in different beer types by applying a combination of stable-isotope dilution assays (SIDAs) and matrix-matched calibration. With limits of detection (LODs) between 0.03 µg/L (alternariol monomethyl ether, AME) and 5.48 µg/L (altenuene, ALT), limits of quantitation (LOQs) between 0.09 µg/L (AME) and 16.24 µg/L (ALT), and recoveries between 72 and 113%, we obtained a sensitive and reliable method, which also covers the emerging toxins alternariol-3-glucoside (AOH-3-G), alternariol-9-glucoside (AOH-9-G), alternariol monomethyl ether-3-glucoside (AME-3-G) and alternariol-3-sulfate (AOH-3-S) and alternariol monomethylether-3-sulfate (AME-3-S). Furthermore, 50 different beer samples were analyzed, showing no contamination with Alternaria toxins apart from tenuazonic acid (TeA) in concentrations between 0.69 µg/L and 16.5 µg/L. According to this study, the exposure towards TeA through beer consumption can be considered as relatively low, as the threshold of toxicological concern (TTC) value of 1500 ng/kg body weight per day might not be reached when consuming reasonable amounts of beer.
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