ArticleRheumatology international2021
Pain is not the major determinant of quality of life in fibromyalgia: results from a retrospective "real world" data analysis of fibromyalgia patients.
Article in Rheumatology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- A Systematic Review and Meta-Analysis Examining the Effect of Mindfulness Based Stress Reduction on Pain Severity and Quality of Life in People Living With Fibromyalgia.European journal of pain (London, England) · 2026Pooled it
- Managing fibromyalgia with complementary and alternative medical exercise: a systematic review and meta-analysis of clinical trials.Rheumatology international · 2022Pooled it
- Clinical outcomes of asynchronous telerehabilitation through a mobile app are equivalent to synchronous telerehabilitation in patients with fibromyalgia: a randomized control study.BMC musculoskeletal disorders · 2025Trial
- Racial Disparities in Pain Among Women with Fibromyalgia: Secondary Data Analysis of Severity, Interference with Function, and Response to Guided Imagery.Journal of integrative and complementary medicine · 2023Trial
- Prevalence of fibromyalgia in Egyptian patients with systemic lupus erythematosus and its impact on health-related quality of life.Advances in rheumatology (London, England) · 2026Article
- Brain-immune correlates of quality of life in adolescents with chronic musculoskeletal pain.Brain, behavior, and immunity · 2026Article
- Disability Assessment with WHODAS 2.0 of People with Fibromyalgia in Poland: A Cross Sectional-Study.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- The Fibromyalgia Decomposition Phenomenon: A Reflexive Thematic Analysis.Behavioral sciences (Basel, Switzerland) · 2024Article
- Coexistence of fibromyalgia syndrome and inflammatory rheumatic diseases, and autonomic cardiovascular system involvement in fibromyalgia syndrome.Clinical rheumatology · 2023Review
- Physical activity and quality of life of patients with fibromyalgia.South African journal of sports medicine · 2023Article
- Effectiveness and adverse effects of the use of mirtazapine as compared to duloxetine for fibromyalgia: real-life data from a retrospective cohort.Rheumatology international · 2022Article
- Exploring the Relationship between Fibromyalgia-Related Fatigue, Physical Activity, and Quality of Life.International journal of environmental research and public health · 2022Article
- Health, Psychological and Demographic Predictors of Depression in People with Fibromyalgia and Osteoarthritis.International journal of environmental research and public health · 2022Article
- Fibromyalgia syndrome: epidemiology, diagnosis and treatment.Reumatologia · 2022Article
- Virtual Reality-Based Therapy Reduces the Disabling Impact of Fibromyalgia Syndrome in Women: Systematic Review with Meta-Analysis of Randomized Controlled Trials.Journal of personalized medicine · 2021Review
- Psychological Flexibility Is Key for Reducing the Severity and Impact of Fibromyalgia.International journal of environmental research and public health · 2021Article
- Role of sexuality in women with chronic pain: Results from an Italian cross-sectional study on chronic headache, fibromyalgia, and vulvodynia.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 9 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify correlates of quality of life (QoL) measured with the Quality of Life Scale (QOLS) in participants of a multidisciplinary day hospital treatment program for fibromyalgia (FM).
methodsIn this cross-sectional, observational study, "real world" data from 480 FM patients including socio-demographics, pain variables and questionnaires such as the SF-36, Beck Depression Inventory (BDI), Multiphasic Pain Inventory (MPI), SCL-90-R and others were categorized according to the components (body structure and function, activities and participation, personal factors, environmental factors) of the International Classification of Functioning (ICF). For every ICF component, a linear regression analysis with QOLS as the dependent variable was computed. A final comprehensive model was calculated on the basis of the results of the five independent analyses.
resultsThe following variables could be identified as main correlates for QoL in FM, explaining 56% of the variance of the QOLS (subscale/questionnaire and standardized beta in parenthesis): depression (- 0.22), pain-related interference with everyday life (- 0.19), general activity (0.13), general health perception (0.11), punishing response from others (- 0.11), work status (- 0.10), vitality (- 0.11) and cognitive difficulties (- 0.12). Pain intensity or frequency was not an independent correlate.
conclusionsMore than 50% of QoL variance could be explained by distinct self-reported variables with neither pain intensity nor pain frequency playing a major role. Therefore, FM treatment should not primarily concentrate on pain but should address multiple factors within multidisciplinary therapy.
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Registered trials
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