Evidence map›Paper›PMID 33666548›Full record

ArticleSICOT-J2021

Predicting neurological deficit in patients with spinal tuberculosis - A single-center retrospective case-control study.

Samarth Mittal, Gagandeep Yadav, Kaustubh Ahuja, Syed Ifthekar, Bhaskar Sarkar, Pankaj Kandwal

Open access · goldAbstract read
In one paragraph

Article in SICOT-J, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
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  8. Utility of clinicoradiological, microbiological, histopathological, and molecular methods in the diagnosis of spinal tuberculosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
  9. Article
  10. Article
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  12. Article
  13. Tuberculosis of the Spinal Cord.Annals of Indian Academy of Neurology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Samarth MittalSenior Resident, AIIMS Rishikesh, 249203 Rishikesh, Uttarakhand, India.ORCID 0000-0003-3528-0949
Gagandeep YadavDepartment of Orthopaedics, AIIMS Rishikesh, 249203 Rishikesh, Uttarakhand, India.
Kaustubh AhujaSenior Resident, AIIMS Rishikesh, 249203 Rishikesh, Uttarakhand, India.
Syed IfthekarSenior Resident, AIIMS Rishikesh, 249203 Rishikesh, Uttarakhand, India.ORCID 0000-0002-3546-5962
Bhaskar SarkarAssistant Professor, AIIMS Rishikesh, 249203 Rishikesh, Uttarakhand, India.ORCID 0000-0002-1317-534X
Pankaj KandwalAdditional Professor, Consultant Spine Surgeon, AIIMS Rishikesh, 249203 Rishikesh, Uttarakhand, India.
All India Institute of Medical Sciences Raipur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdentifying the risk factors for the neurological deficit in spine tuberculosis would help surgeons in deciding on early surgery, thus reducing the morbidity related to neurological deficit. The main objective of our study was to predict the risk of neurological deficit in patients with spinal tuberculosis (TB).

methodsThe demographic, clinical, radiological (X-ray and MRI) data of 105 patients with active spine TB were retrospectively analyzed. Patients were divided into two groups - with a neurological deficit (n = 52) as Group A and those without deficit (n = 53) as Group B. Univariate and multivariate logistic regression analysis was used to predict the risk factors for the neurological deficit.

resultsThe mean age of the patients was 38.1 years. The most common location of disease was dorsal region (35.2%). Paradiscal (77%) was the most common type of involvement. A statistically significant difference (p < 0.05) was noted in the location of disease, presence of cord compression, kyphosis, cord oedema, loss of CSF anterior to the cord, and degree of canal compromise or canal encroachment between two groups. Multivariate analysis revealed kyphosis > 30° (OR - 3.92, CI - 1.21-12.7, p - 0.023), canal encroachment > 50% (OR - 7.34, CI - 2.32-23.17, p - 0.001), and cord oedema (OR - 11.93, CI - 1.24-114.05, p - 0.03) as independent risk factors for predicting the risk of neurological deficit.

conclusionKyphosis > 30°, cord oedema, and canal encroachment (>50%) significantly predicted neurological deficit in patients with spine TB. Early surgery should be considered with all these risk factors to prevent a neurological deficit.

Indexed as

Neurologic deficitPott’s paraplegiaRisk factorsSpinal tuberculosis

Identifiers

PMID33666548
PMCPMC7934611
OpenAlexW3135586115

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.