Evidence map›Paper›PMID 33666124›Full record

ArticleNeurocase2021

Unexpected absence of aphasia following left temporal hemorrhage: a case study with functional neuroimaging to characterize the nature of atypical language localization.

Sarah M Schneck, Jillian L Entrup, Melissa C Duff, Stephen M Wilson

Open access · greenAbstract readCase Reports
In one paragraph

Article in Neurocase, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Situating word deafness within aphasia recovery: A case report.Cortex; a journal devoted to the study of the nervous system and behavior · 2024
    Article
  4. Recovery from aphasia in the first year after stroke.Brain : a journal of neurology · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sarah M SchneckDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0001-9447-4431
Jillian L EntrupDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0001-8822-0005
Melissa C DuffDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0003-1759-3634
Stephen M WilsonDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0001-9884-2852
Vanderbilt University Medical Center · US

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
Neural Correlates of Recovery from Aphasia After StrokeR01DC013270 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Stephen M Wilson, Michael R de Riesthal · 2014 to 2026
$6.3M
Molecular mechanisms mediating the soft tissue attachment to teethR01DE031270 · NIDCR · STANFORD UNIVERSITY · PI Jill A Helms · 2023 to 2026
$2.9M
NICHD NIH HHS P50 HD103537NIDCD NIH HHS R01 DC013270NIDCR NIH HHS R01 DE031270
6 · The paper itself

Abstract

Unexpected absence of aphasia after left-hemisphere perisylvian damage is often assumed to reflect right-hemisphere language lateralization, but other potential explanations include bilateral language representation, or sparing of critical left-hemisphere regions due to individual variability. We describe the case of a left-handed gentleman who presented with no aphasia after a left temporal hemorrhage. We used functional neuroimaging to determine how his language network had been spared. In this case, we observed unequivocal right-hemisphere lateralization of language function, explaining his lack of aphasia. We discuss the variability of language organization and highlight outstanding questions about the implications of damage in different scenarios.

Indexed as

AphasiaLanguageFunctional LateralityFunctional NeuroimagingHemorrhageHumansMagnetic Resonance ImagingAphasiaatypical language organizationbilateral languagefMRIright-lateralized language

Identifiers

PMID33666124
PMCPMC8026574
OpenAlexW3135468604

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.